{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T03:17:47Z","timestamp":1779333467400,"version":"3.51.4"},"reference-count":30,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Patient-reported outcome measures (PROM) on quality of life (QOL) for early-stage floor of mouth carcinoma (FOM-CA) undergoing surgical resection and split-thickness skin graft (STSG) reconstruction have not been established. We have performed a cross-sectional QOL analysis of such patients to define functional postoperative outcomes. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Patients with pathologic stage T1\/T2 FOM-CA who underwent resection and STSG reconstruction at a tertiary academic cancer center reported outcomes with the University of Washington QOL (v4) questionnaire after at least 6 months since surgery. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Twenty-four out of 49 eligible patients completed questionnaires with a mean follow-up of 41 months (range: 6\u201388). Subsites of tumor involvement\/resection included the following: (1) lateral FOM (L-FOM) (&lt;i&gt;n&lt;\/i&gt; = 17), (2) anterior FOM (A-FOM) (&lt;i&gt;n&lt;\/i&gt; = 4), and (3) alveolar ridge with FOM, all of whom underwent lateral marginal mandibulectomy (MM-FOM) (&lt;i&gt;n&lt;\/i&gt; = 3). All patients reported swallowing scores of 70 (\u201cI cannot swallow certain solid foods\u201d) or better. Ninety-six percent (23\/24) reported speech of 70 (\u201cdifficulty saying some words, but I can be understood over the phone\u201d) or better. A-FOM patients reported worse chewing than L-FOM patients (mean: 50.0 vs. 85.3; &lt;i&gt;p&lt;\/i&gt; = 0.01). All 4 A-FOM patients reported a low chewing score of 50 (\u201cI can eat soft solids but cannot chew some foods\u201d). Otherwise, there were no significant differences between subsite groups in swallowing, speech, or taste. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; STSG reconstructions for pathologic T1\u2013T2 FOM-CA appear to result in acceptable PROM QOL outcomes with the exception of A-FOM tumors having worse chewing outcomes. <\/jats:p>","DOI":"10.1159\/000512085","type":"journal-article","created":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T12:35:22Z","timestamp":1613219722000},"page":"151-158","source":"Crossref","is-referenced-by-count":4,"title":["Patient-Reported Outcomes of Split-Thickness Skin Grafts for Floor of Mouth Cancer Reconstruction"],"prefix":"10.1159","volume":"83","author":[{"given":"Andrew R.","family":"Larson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine 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