{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:26:58Z","timestamp":1745468818630,"version":"3.40.4"},"reference-count":9,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background Purpose:&lt;\/i&gt;&lt;\/b&gt; Vein of Galen aneurysmal malformations (VGAM) may carry life-threatening and catastrophic sequelae in children. Their clinical presentations are differently variable between cardiac and cerebral syndromes. There may be a possible relationship between the Galenic angioarchitecture and the clinical presentation. We aimed to study the effect of the venous outflow impairment on the incidence of high-flow heart failure and the incidence of hydrocephalus. &lt;b&gt;&lt;i&gt;Materials and Methods:&lt;\/i&gt;&lt;\/b&gt; The angiographies of 21 patients with true VGAM have been studied. MR angiography, 3-dimensional CT angiogram (3D CTA), and conventional digital subtraction angiography were performed for all patients with true VGAM. Transarterial embolization was done in 1 or more sessions for all cases. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Among the 21 cases, 14 cases were mural type, 5 cases were choroidal type, and 2 cases were mixed. Hydrocephalus was observed more in infants (92.3%), mural types (92.9%), giant and supergiant (87.5%) aneurysms, and in cases with persistent limbic circle (90.91%). All cases of hydrocephalus were associated with significant stenosis (&amp;#x3e;70%) of the Falcine sinus draining system (100%). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Significant stenosis (&amp;#x3e;70%) of the draining sinus is a significant factor for VGAM aneurysmal enlargement and occurrence of hydrocephalus. Probably, venous outflow impairment decreases the incidence of high-flow heart failure and increases the incidence of hydrocephalus. <\/jats:p>","DOI":"10.1159\/000512213","type":"journal-article","created":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T22:01:09Z","timestamp":1610575269000},"page":"344-350","source":"Crossref","is-referenced-by-count":1,"title":["The Impact of Angiographic Geometry on the Clinical Presentation of True Vein of Galen Aneurysmal Malformations"],"prefix":"10.1159","volume":"55","author":[{"given":"Tamer","family":"Hassan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waleed F.","family":"El-Saadany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,1,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1946.02300170035005"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000324911"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000237445.39514.16"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.13676"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyy100"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182417be3"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/BF00698838"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/bf00298261"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/2152-7806.109657"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512213","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512213","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:14:52Z","timestamp":1745424892000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":9,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,1,28]]},"published-print":{"date-parts":[[2021,2,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000512213","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"type":"print","value":"1016-2291"},{"type":"electronic","value":"1423-0305"}],"subject":[],"published":{"date-parts":[[2020]]}}}