{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T17:09:25Z","timestamp":1784221765407,"version":"3.55.0"},"reference-count":42,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; The impact of heterogeneity on gender difference for achieving clinically meaningful weight loss (cmWL) remains unclear. Here, we explored the potential gender differences in factors associated with cmWL. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A total of 60,668 participants with body mass index (BMI) \u226525 kg\/m&lt;sup&gt;2&lt;\/sup&gt; at study entry and available BMI values at follow-up were included in this study. cmWL was defined as a weight loss of \u22655% from the study entry to follow-up. The associations of social-demographic factors, personal history of chronic diseases, lifestyle behaviors, and history of BMI with cmWL were evaluated using logistic regression models. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; During a median follow-up of 9.13 years, 26.6% of the participants had a cmWL (30.8% for females vs. 23.1% in males; &lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.001). Participants with older age, obesity at study entry, being more physical activity compared to 10 years ago, being relapsed smokers or consistent current smokers, having a history of chronic diseases (i.e., diabetes, osteoporosis, and stroke), cancer diagnosis during the study period, and more than 10-year follow-up were more likely to achieve cmWL in both males and females (all &lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). The new smoking quitters and participants with less active in physical activity compared to 10 years ago were less likely to achieve cmWL in both males and females (all &lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). Specifically, males with a history of emphysema were more likely to reach cmWL, and for females, those being overweight at 20 years old and current drinkers were more likely to reach cmWL (&lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). Sensitivity analyses demonstrated similar results. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Age, BMI status, physical activity, smoking status, family income, and health status were independent factors in males and females for weight management. However, further well-designed prospective studies are warranted to confirm our findings. <\/jats:p>","DOI":"10.1159\/000512294","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T22:00:33Z","timestamp":1608674433000},"page":"108-120","source":"Crossref","is-referenced-by-count":16,"title":["Gender Differences in Factors Associated with Clinically Meaningful Weight Loss among Adults Who Were Overweight or Obese: A Population-Based Cohort Study"],"prefix":"10.1159","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7632-3648","authenticated-orcid":false,"given":"Ji-Bin","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Yu","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Fen","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Dong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60105-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065174"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2010.04.011"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr1606602"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s40880-018-0275-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2012.01010.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/j.1550-8528.1995.tb00466.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/nu11071667"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000479972"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s40880-019-0390-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2012.01.005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e31828ba942"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2005.00166.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2007.07.017"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000362196"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s40608-016-0098-0"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.118"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3945\/jn.109.120808"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20830"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/s40880-019-0368-6"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12241"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1177\/1557988316654866"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.2013-0220"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12622"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1159\/000281833"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2011.278"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12120"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(00)00097-0"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.bodyim.2008.11.004"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1177\/1557988314567223"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5868-8-20"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1177\/1363459311425512"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1987.tb36195.x"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802821"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199103143241106"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122219"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-14-926"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-017-0286-5"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2015.127"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1037\/hea0000607"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1186\/s40814-016-0102-y"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20967"}],"container-title":["Obesity Facts"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512294","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:16:01Z","timestamp":1745424961000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,22]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,3,4]]},"published-print":{"date-parts":[[2021,2,28]]}},"URL":"https:\/\/doi.org\/10.1159\/000512294","archive":["Portico"],"relation":{},"ISSN":["1662-4025","1662-4033"],"issn-type":[{"value":"1662-4025","type":"print"},{"value":"1662-4033","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,22]]}}}