{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:27:05Z","timestamp":1745468825059,"version":"3.40.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T00:00:00Z","timestamp":1614816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T00:00:00Z","timestamp":1614816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Gastroenterol"],"abstract":"<jats:p>We present the case of a 35-year-old man with intractable nausea, vomiting, and severe anemia. A computed tomography (CT) scan of the chest, abdomen, and pelvis showed a circumferential lesion thickening of up to 3.5 cm at the level of the third portion of the duodenum. No aortocaval, retroperitoneal lymphadenopathy, nor secondary lesion was observed. Esophagogastroduodenoscopy (EGD) revealed a circumferential mass within the third portion of the duodenum. Histopathology of biopsy materials from the duodenal mass showed it most likely to be a poorly differentiated adenocarcinoma. The patient underwent a subtotal stomach-preserving pancreaticoduodenectomy with regional lymph node dissection. Histologically, tumor cells with basophilic cytoplasm and pleomorphic nuclei showed a solid pattern, and expressed CD30 and SALL4 immunohistochemically, leading to a diagnosis of embryonal carcinoma-like tumor. No other primary tumor could be identified, and the location of the tumor, mainly on the mucosal surface, suggested a duodenal origin. The UICC TNM staging was T3N2M0, stage IIB. This is a rare case of primary duodenal carcinoma with features of embryonal carcinoma. <\/jats:p>","DOI":"10.1159\/000512421","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T16:24:48Z","timestamp":1616516688000},"page":"269-275","source":"Crossref","is-referenced-by-count":1,"title":["Primary Duodenal Carcinoma with Embryonal Carcinoma Features in a Young Man"],"prefix":"10.1159","volume":"15","author":[{"given":"Naoto","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kota","family":"Washimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Murakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuto","family":"Kamioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Ueno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Kishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Rino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munetaka","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soichiro","family":"Morinaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,3,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-10-0328"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v8.i3.212"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21332"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/BF01072468"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0b013e31803240e6"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i4.730"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(76)90374-5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65947-0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.07.045"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/2348-3113.152335"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.07.044"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.53.3014"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2016.06.021"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10018-1200"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-016-1964-6"}],"container-title":["Case Reports in Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:16:56Z","timestamp":1745425016000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,4]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,5,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000512421","archive":["Portico"],"relation":{},"ISSN":["1662-0631"],"issn-type":[{"type":"electronic","value":"1662-0631"}],"subject":[],"published":{"date-parts":[[2021,3,4]]}}}