{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T01:18:38Z","timestamp":1794619118407,"version":"4.9.1"},"reference-count":41,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T00:00:00Z","timestamp":1608163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T00:00:00Z","timestamp":1608163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Background:<\/i><\/b> Currently, the two most common bariatric procedures are laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). Long-term data comparing the two interventions in terms of their effect on body composition and bone mass density (BMD) are scarce. <b><i>Objective:<\/i><\/b> The aim of this study was to assess body composition and BMD at least 5 years after LSG and LRYGB. <b><i>Setting:<\/i><\/b> Department of Endocrinology and Nutrition, St. Claraspital Basel and St. Clara Research Ltd., Basel, Switzerland. <b><i>Methods:<\/i><\/b>Bariatric patients at least 5 years after surgery (LSG or LRYGB) were recruited, and body composition and BMD were measured by means of dual-energy X-ray absorptiometry. Data from body composition before surgery were included in the analysis. Blood samples were taken for determination of plasma calcium, parathyroid hormone, vitamin D<sub>3<\/sub>, alkaline phosphatase, and C-terminal telopeptide, and the individual risk for osteoporotic fracture assessed by the Fracture Risk Assessment Tool score was calculated. After surgery, all patients received multivitamins, vitamin D<sub>3<\/sub>, and zinc. In addition, LRYGB patients were prescribed calcium. <b><i>Results:<\/i><\/b> A total of 142 patients were included, 72 LSG and 70 LRYGB, before surgery: median body mass index 43.1, median age 45.5 years, 62.7% females. Follow-up after a median of 6.7 years. For LRYGB, the percentage total weight loss at follow-up was 26.3% and for LSG 24.1% (<i>p<\/i> = 0.243). LRYGB led to a slightly lower fat percentage in body composition. At follow-up, 45% of both groups had a T score at the femoral neck below \u20131, indicating osteopenia. No clinically relevant difference in BMD was found between the groups. <b><i>Conclusions:<\/i><\/b>At 6.7 years after surgery, no difference in body composition and BMD between LRYGB and LSG was found. Deficiencies and bone loss remain an issue after both interventions and should be monitored. <\/jats:p>","DOI":"10.1159\/000512450","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T22:01:47Z","timestamp":1608242507000},"page":"131-140","source":"Crossref","is-referenced-by-count":21,"title":["Long-Term Effects of Laparoscopic Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Body Composition and Bone Mass Density"],"prefix":"10.1159","volume":"14","author":[{"given":"Julian","family":"B\u00fchler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvan","family":"Rast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Beglinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Peterli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Gebhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u00a0Christin","family":"Meyer-Gerspach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3134-2743","authenticated-orcid":false,"given":"Bettina\u00a0Karin","family":"W\u00f6lnerhanssen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2020,12,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199503093321001"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.46.10.1579"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.675355"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2015.2398"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002407"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2020.0087"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1381\/096089206779319347"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-011-0538-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.89"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2012.11.007"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-1596"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2015.07.002"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-015-1792-6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2019.5917\/2018"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-006-0172-4"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4158\/EP.16.S3.1"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2005.11.024"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2269"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-016-0332-0"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204320"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2009.260"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i3794"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-255X(01)00086-5"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-016-2114-3"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2004.01.015"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-007-0543-5"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/PL00005830"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1080\/00031305.2018.1527253"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-0318-1"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1111\/insr.12243"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v080.i01"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-020-04654-6"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-009-0045-y"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200636030-00005"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068716"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-010-1501-1"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-017-2546-4"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2016.11.029"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-017-2748-9"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.20897"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-010-0141-0"}],"container-title":["Obesity 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