{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:31:08Z","timestamp":1747193468017,"version":"3.40.5"},"reference-count":10,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Immunotherapy as wart treatment has been proposed as a successful and well-tolerated treatment option. However,  as their action is not confined to the site of injection, the activation of the immune system in a way may alter the immune state of the patient. &lt;b&gt;&lt;i&gt;Case Presentation:&lt;\/i&gt;&lt;\/b&gt; A case of 29-year-old patient who experienced psoriasis exacerbation and psoriatic arthritis within days following &lt;i&gt;Candida&lt;\/i&gt; antigen immunotherapy injection for resistant filiform wart management. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; &lt;i&gt;Candida&lt;\/i&gt; antigen injection may cause psoriasis exacerbation, as TNF\u03b1 and subsequent T-helper 1 induction is crossroad in both psoriasis and &lt;i&gt;Candida&lt;\/i&gt; antigen immunotherapy. Therefore, we report this case to state that besides the effectiveness of &lt;i&gt;Candida&lt;\/i&gt; antigen for wart therapy, caution should be considered if used in patients who are susceptible to psoriasis with meticulous follow-up or better to apply an alternative treatment option. <\/jats:p>","DOI":"10.1159\/000512568","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T22:00:41Z","timestamp":1611266441000},"page":"212-215","source":"Crossref","is-referenced-by-count":1,"title":["Psoriasis Exacerbation after &lt;b&gt;&lt;i&gt;Candida&lt;\/i&gt;&lt;\/b&gt; Antigen Immunotherapy Injection"],"prefix":"10.1159","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9068-9475","authenticated-orcid":false,"given":"Sameh Magdy","family":"Sarsik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Hamdy","family":"Soliman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12352"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2013.10.014"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-013-0018-8"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.5.589"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.350"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.07.003"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/01206501-200503000-00008"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S136986"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03410.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-016-0564-5"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512568","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512568","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:17:52Z","timestamp":1745425072000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,4,30]]},"published-print":{"date-parts":[[2021,5,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000512568","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"type":"print","value":"2296-9195"},{"type":"electronic","value":"2296-9160"}],"subject":[],"published":{"date-parts":[[2021]]}}}