{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T04:38:09Z","timestamp":1779943089209,"version":"3.53.1"},"reference-count":20,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>Purpose: To explore the potential use of ultra-wide-field (UWF) imaging for screening of cytomegalovirus retinitis (CMVR) in AIDS patients. Methods: Ninety-four patients whose CD4 count was below 200 cells\/\u03bcL were enrolled in a prospective study. Each patient underwent UWF imaging and indirect ophthalmoscopy. The main outcome measures were the concordance and detection rates of these 2 approaches and the sensitivity and specificity of UWF imaging. Results: Twenty-seven eyes in 18 patients were diagnosed with CMVR by the indirect ophthalmoscopy. UWF imaging missed the diagnosis in 1 eye because of a zone 3 CMVR lesion. The UWF image showed several CMVR patterns and locations: hemorrhagic necrotizing lesion, granular lesion, frosted branch angiitis, and optic neuropathy lesion. The concordance of the 2 approaches was excellent for the diagnosis of CMVR, classification of CMVR pattern, and location of CMVR. The detection rates of UWF imaging and indirect ophthalmoscopy were 14.0% (26\/186; 95% CI 0.089\u20130.190) and 14.5% (27\/186; 95% CI 0.094\u20130.196), respectively (p = 1.000). The sensitivity and specificity of UWF imaging were 96.3 and 100%, respectively. Conclusions: UWF imaging is capable of documentation of different CMVR lesions and AIDS-related CMVR screening when examination by an ophthalmologist is not available. <\/jats:p>","DOI":"10.1159\/000512634","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T22:00:31Z","timestamp":1604008831000},"page":"334-338","source":"Crossref","is-referenced-by-count":7,"title":["Utility of Ultra-Wide-Field Imaging for Screening of AIDS-Related Cytomegalovirus Retinitis"],"prefix":"10.1159","volume":"244","author":[{"given":"Kui-Fang","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Jie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian-Yong","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jun","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Wei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Bin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2020,10,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph13010030"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2015.29.4.241"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/112067210601600511"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu648"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16500-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-312191"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2016-308556"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136747"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit494"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.4766"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2018.10.001"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2019.1595671"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s40135-018-0173-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20160126-01"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70174-8"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20100430-03"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S2589-7500(19)30123-2"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-019-01074-z"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-09891-x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.5696"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/oph\/article-pdf\/244\/4\/334\/3974218\/000512634.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/oph\/article-pdf\/244\/4\/334\/3974218\/000512634.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:05:01Z","timestamp":1745424301000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,29]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,9,1]]},"published-print":{"date-parts":[[2021,9,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000512634","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,29]]}}}