{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T21:11:25Z","timestamp":1776287485459,"version":"3.50.1"},"reference-count":17,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> Prenatal suprarenal lesions represent diverse pathologies. This study investigated prenatal imaging features and regression patterns associated with specific lesion diagnoses. <b><i>Methods:<\/i><\/b> This is a multicenter retrospective review of fetuses with prenatally diagnosed suprarenal lesions between 2001 and 2019. Prenatal ultrasound and MRI characteristics, postnatal imaging, and clinical course were reviewed<i>.<\/i> Prenatal imaging findings were compared by the most common diagnoses and regression patterns. <b><i>Results:<\/i><\/b> Forty-four fetuses were prenatally diagnosed with suprarenal lesions. Diagnoses included pulmonary sequestration (<i>n<\/i> = 12; 27.3%), adrenal hemorrhage (<i>n<\/i> = 12; 27.3%), upper quadrant cyst (including 2 duplication cysts, 1 splenic cyst, and 3 indeterminate cysts), neuroblastoma (<i>n<\/i> = 4), adrenal hyperplasia (<i>n<\/i> = 3), bilateral adrenal calcifications (<i>n<\/i> = 1), and indeterminate lesions (<i>n<\/i> = 6). Sequestrations were uniformly left-sided (100 vs. 50%; <i>p<\/i> = 0.014) and diagnosed earlier in gestation than adrenal hemorrhages (<i>p<\/i> = 0.025). Sequestrations were also significantly more likely to have a prenatal feeding vessel (<i>p<\/i> = 0.005), low T1 MRI signal (<i>p<\/i> = 0.015), and no MRI blood products (<i>p<\/i> = 0.018) compared to adrenal hemorrhages. When comparing all 44 patients, a prenatal feeding vessel and low T1 signal on prenatal MRI were significantly associated with lesion persistence (<i>p<\/i> = 0.003; <i>p<\/i> = 0.044). <b><i>Discussion\/Conclusion:<\/i><\/b> Imaging findings on prenatal ultrasound and MRI aid in the diagnosis of suprarenal lesions, including differentiating pulmonary sequestrations and adrenal hemorrhages. <\/jats:p>","DOI":"10.1159\/000512689","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T17:11:10Z","timestamp":1616519470000},"page":"235-242","source":"Crossref","is-referenced-by-count":5,"title":["Prenatal Imaging Diagnosis of Suprarenal Lesions"],"prefix":"10.1159","volume":"48","author":[{"given":"Stefanie P.","family":"Lazow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle M.","family":"Richman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrice","family":"Dionigi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Staffa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol B.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry L.","family":"Buchmiller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/spsu.2000.7560"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-015-3470-1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1148\/131.2.453"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1997.16.2.75"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1323162"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.33.5.895"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2011.12.1.52"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2018.1471679"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000047998"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-009-2531-7"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3468(00)80020-2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-019-04590-2"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-37268-1"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-018-4362-x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1668576"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050348"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.04.022"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512689","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:05:49Z","timestamp":1745424349000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,4,8]]},"published-print":{"date-parts":[[2021,4,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000512689","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.14229131","asserted-by":"subject"}]},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}