{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T22:38:54Z","timestamp":1767998334138,"version":"3.49.0"},"reference-count":15,"publisher":"S. Karger AG","issue":"7-8","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> The goal was to determine risk factors for Clavien-Dindo (CD) grade \u22652 complications, with special focus on early postoperative systemic inflammatory response syndrome (SIRS), for flexible ureteroscopy (fURS). <b><i>Materials and Methods:<\/i><\/b> A retrospective monocentric statistical analysis relating to 32 factors was performed with the \u03c7<sup>2<\/sup> test, Mann-Whitney U tests, and multivariate logistic regression. <b><i>Results:<\/i><\/b> In total, 416 consecutive fURS performed between September 2013 and June 2017 were analyzed; 283 (68.03%) of these were for stone surgery and 133 (31.97%) for diagnostic purposes. In 43 cases (10.34%), CD \u22652 occurred; 31 cases (72.09%) of these were SIRS. On multivariate logistic regression, positive preoperative urine culture and steep pyelographic and CT-based infundibulopelvic angle (IPA) have been confirmed as independent risk factors for both CD \u22652 and SIRS. Greater maximal median stone diameter and female gender were significantly associated only with a higher CD \u22652 prevalence, but not with SIRS. The influence of ureteral access sheath (UAS) on CD \u2265 2 or SIRS occurrence could not be confirmed on multivariate analysis. Perioperative antibiotic prophylaxis for patients with negative urine culture showed no difference regarding SIRS prevalence. <b><i>Conclusion:<\/i><\/b> Steep CT-based IPA can be considered as a new radiologic predictor of complicated postoperative course and SIRS. The role of UAS as well as indications for perioperative antibiotic prophylaxis should be determined in prospective studies. <\/jats:p>","DOI":"10.1159\/000512892","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T21:05:16Z","timestamp":1617051916000},"page":"611-618","source":"Crossref","is-referenced-by-count":4,"title":["Risk Factors for a Complicated Postoperative Course in Flexible Ureteroscopy"],"prefix":"10.1159","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6880-3190","authenticated-orcid":false,"given":"Tomasz","family":"Ozimek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Hochguertel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie C.","family":"Hupe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian P.","family":"Struck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith R.","family":"Wiessmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel S.","family":"Merseburger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario W.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,2,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13520"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.09.096"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1089\/end.2006.20.179"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(01)63699-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.6.1644"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/end.2018.0147"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2379-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1089\/end.2019.0317"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-015-1582-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193600"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1089\/end.2018.0177"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12502"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000509"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000494362"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512892","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/512892","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:08:26Z","timestamp":1745424506000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000512892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":15,"journal-issue":{"issue":"7-8","published-online":{"date-parts":[[2021,6,30]]},"published-print":{"date-parts":[[2021,7,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000512892","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}