{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:56:53Z","timestamp":1790740613243,"version":"4.1.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The application of computational technology to head and neck cytology material has been explored experimentally in several areas with a variety of potential applications. &lt;b&gt;&lt;i&gt;Summary:&lt;\/i&gt;&lt;\/b&gt; This review summarizes the application of these techniques to the diagnosis of thyroid, salivary gland, and other head and neck fine-needle aspiration specimens. Current limitations and potential future applications in diagnosis are discussed along with the possibilities for therapeutic applications of computational methodology. &lt;b&gt;&lt;i&gt;Key Message:&lt;\/i&gt;&lt;\/b&gt; Particularly promising applications include resolving diagnostic uncertainty in indeterminate thyroid aspirates and assessing the tumor microenvironment in response to immunotherapy for squamous cell carcinoma. <\/jats:p>","DOI":"10.1159\/000513286","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T21:05:54Z","timestamp":1617051954000},"page":"330-334","source":"Crossref","is-referenced-by-count":5,"title":["Applications of Computational Pathology in Head and Neck Cytopathology"],"prefix":"10.1159","volume":"65","author":[{"given":"Trang K.","family":"Lollie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7768-3901","authenticated-orcid":false,"given":"Jeffrey F.","family":"Krane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4137\/BECB.S31601"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22120"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3892\/or.15.4.1023"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4103\/jpi.jpi_43_18"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.10355"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(89)80226-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20011001)92:7%3c1818::aid-cncr1698%3e3.0.co;2-u"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.197579"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097-0142(19980425)84:2%3c115::aid-cncr8%3e3.0.co;2-o"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23880"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4103\/JOC.JOC_87_16"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23611"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22238"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/jpi.jpi_25_19"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000346715"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200211000-00014"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000147950.35923.ba"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22236"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/513286","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/513286","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:13:10Z","timestamp":1745424790000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000513286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":18,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,8,18]]},"published-print":{"date-parts":[[2021,8,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000513286","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"value":"0001-5547","type":"print"},{"value":"1938-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}