{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T23:01:27Z","timestamp":1781478087184,"version":"3.54.1"},"reference-count":17,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Surg"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> The peritoneal cancer index (PCI) is one of the most important prognostic factors in patients with peritoneal metastases from colorectal cancer undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC). The PCI is determined during laparotomy by 2 experienced surgeons and plays a major role in the decision to proceed with CRS-HIPEC. The primary objective of this study was to determine the accuracy of the surgical PCI (sPCI) by comparing it with the PCI confirmed by the pathologist (pPCI). <b><i>Methods:<\/i><\/b> All consecutive patients who underwent CRS-HIPEC for colorectal peritoneal metastases between February 2015 and June 2018 were identified. Relevant patient- and tumor-related characteristics were collected. <b><i>Results:<\/i><\/b> In total, 119 patients were included, 60 males (50.4%). The median age was 64 (IQR 55\u201371). The median sPCI (sPCI = 11, IQR 6\u201316) was significantly higher than the median pPCI (pPCI = 8, IQR 3\u201313, <i>p<\/i> &#x3c; 0.001). The total pPCI was lower than the total sPCI in 80 patients (67.2%). In 21 patients (17.6%), the sPCI was overestimated with \u22655 points. Small lesions are more likely to be negative. In patients that underwent resection of their primary tumor prior to CRS-HIPEC, the difference between the sPCI and pPCI was significantly larger (<i>p<\/i> &#x3c; 0.05). <b><i>Conclusions:<\/i><\/b> Surgical calculation of the PCI often results in overestimation. Far-reaching consequences are tied to the macroscopic evaluation of the sPCI, but this evaluation seems not very reliable. <\/jats:p>","DOI":"10.1159\/000513353","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T21:06:01Z","timestamp":1617051961000},"page":"205-211","source":"Crossref","is-referenced-by-count":36,"title":["The Accuracy of the Surgical Peritoneal Cancer Index in Patients with Peritoneal Metastases of Colorectal Cancer"],"prefix":"10.1159","volume":"38","author":[{"given":"Nadine L.","family":"de Boer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra R.M.","family":"Brandt-Kerkhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva V.E.","family":"Madsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Doukas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis","family":"Verhoef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacobus W.A.","family":"Burger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199501000-00004"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/309417"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199502000-00002"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7800-2-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9185-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-1247-5_23"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2006.03.002"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-015-4627-8"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21937"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2012.03.008"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097-0142(20000115)88:2%3c358::aid-cncr16%3e3.0.co;2-o"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-3145-9"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-014-2801-y"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25106"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9713"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-019-07219-9"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-3647-0"}],"container-title":["Digestive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/513353","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/513353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:13:50Z","timestamp":1745424830000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000513353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,6,8]]},"published-print":{"date-parts":[[2021,6,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000513353","archive":["Portico"],"relation":{},"ISSN":["0253-4886","1421-9883"],"issn-type":[{"value":"0253-4886","type":"print"},{"value":"1421-9883","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}