{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:59:39Z","timestamp":1769169579704,"version":"3.49.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Background:<\/i><\/b> The mini-Addenbrooke\u2019s Cognitive Examination (m-ACE) is a brief cognitive battery that assesses 5 subdomains of cognition (attention, memory, verbal fluency, visuospatial abilities, and memory recall). It is scored out of 30 and can be administered in under 5 min providing a quick screening tool for assessment of cognition. <b><i>Objectives:<\/i><\/b> We aimed to adapt the m-ACE in Arabic speakers in Egypt and to validate it in dementia patients to provide cutoff scores. <b><i>Methods:<\/i><\/b> We included 37 patients with dementia (Alzheimer\u2019s disease [<i>n<\/i> = 25], vascular dementia [<i>n<\/i> = 8], and dementia with Lewy body [<i>n<\/i> = 4]) and 43 controls. <b><i>Results:<\/i><\/b> There was a statistically significant difference (<i>p<\/i> &#x3c; 0.001) on the total m-ACE score between dementia patients (mean 10.54 and standard deviation [SD] 5.83) and controls (mean 24.02 and SD 2.75). There was also a statistically significant difference between dementia patients and controls on all sub-score domains of the m-ACE (<i>p<\/i> &#x3c; 0.05). Performance on the m-ACE significantly correlated with both the Mini-Mental State Examination (MMSE) and the Addenbrooke\u2019s Cognitive Examination-III (ACE-III). Using a receiver operator characteristic curve, the optimal cutoff score for dementia on the m-ACE total score was found to be 18 (92% sensitivity, 95% specificity, and 94% accuracy). <b><i>Conclusions:<\/i><\/b> We adapted the m-ACE in Arabic speakers in Egypt and provided objective validation of it as a screening tool for dementia, with high sensitivity, specificity, and accuracy. <\/jats:p>","DOI":"10.1159\/000513411","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T07:32:24Z","timestamp":1613547144000},"page":"611-616","source":"Crossref","is-referenced-by-count":6,"title":["Adaptation and Validation of the Mini-Addenbrooke\u2019s Cognitive Examination in Dementia in Arabic Speakers in Egypt"],"prefix":"10.1159","volume":"49","author":[{"given":"Tarik","family":"Qassem","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed S.","family":"Khater","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer","family":"Emara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doha","family":"Rasheedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heba M.","family":"Tawfik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed S.","family":"Mohammedin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad F.","family":"Tolba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heba G.","family":"Saber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Aly El-Gabry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Abdel Aziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2011.173"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000351671"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2018.06.003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.43.11.2412-a"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1975.00490510088009"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/01.xme.0000457267.05731.0f"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1963.03060120024016"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/9.3_part_1.179"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/0891988719841726"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12417"}],"container-title":["Dementia and Geriatric Cognitive Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/513411","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/513411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:14:13Z","timestamp":1745424853000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000513411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":10,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,4,8]]},"published-print":{"date-parts":[[2021,4,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000513411","archive":["Portico"],"relation":{},"ISSN":["1420-8008","1421-9824"],"issn-type":[{"value":"1420-8008","type":"print"},{"value":"1421-9824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}