{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T17:09:29Z","timestamp":1776272969304,"version":"3.50.1"},"reference-count":12,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> We analyzed whether the coronavirus disease 2019 (COVID-19) crisis affected acute stroke care in our center during the first 2 months of lockdown in Spain. <b><i>Methods:<\/i><\/b> This is a single-center, retrospective study. We collected demographic, clinical, and radiological data; time course; and treatment of patients meeting the stroke unit admission criteria from March 14 to May 14, 2020 (COVID-19 period group). Data were compared with the same period in 2019 (pre-COVID-19 period group). <b><i>Results:<\/i><\/b> 195 patients were analyzed; 83 in the COVID-19 period group, resulting in a 26% decline of acute strokes and transient ischemic attacks (TIAs) admitted to our center compared with the previous year (<i>p<\/i> = 0.038). Ten patients (12%) tested positive for PCR SARS-CoV-2. The proportion of patients aged 65 years and over was lower in the COVID-19 period group (53 vs. 68.8%, <i>p<\/i> = 0.025). During the pandemic period, analyzed patients were more frequently smokers (27.7 vs. 10.7%, <i>p<\/i> = 0.002) and had less frequently history of prior stroke (13.3 vs. 25%, <i>p<\/i> = 0.043) or atrial fibrillation (9.6 vs. 25%, <i>p<\/i> = 0.006). ASPECTS score was lower (9 [7\u201310] vs. 10 [8\u201310], <i>p<\/i> = 0.032), NIHSS score was slightly higher (5 [2\u201314] vs. 4 [2\u20138], <i>p<\/i> = 0.122), onset-to-door time was higher (304 [93\u2013760] vs. 197 [91.25\u2013645] min, <i>p<\/i> = 0.104), and a lower proportion arrived within 4.5 h from onset of symptoms (43.4 vs. 58%, <i>p<\/i> = 0.043) during the CO\u00adVID-19 period. There were no differences between proportion of patients receiving recanalization treatment (intravenous thrombolysis and\/or mechanical thrombectomy) and in-hospital delays. <b><i>Conclusion:<\/i><\/b> We observed a reduction in the number of acute strokes and TIAs admitted during the COVID-19 period. This drop affected especially elderly patients, and despite a delay in their arrival to the emergency department, the proportion of patients treated with recanalization therapies was preserved. <\/jats:p>","DOI":"10.1159\/000514140","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T21:07:53Z","timestamp":1617052073000},"page":"310-316","source":"Crossref","is-referenced-by-count":18,"title":["Acute Stroke Care during the COVID-19 Pandemic: Reduction in the Number of Admissions of Elderly Patients and Increase in Prehospital Delays"],"prefix":"10.1159","volume":"50","author":[{"given":"Gabriel","family":"Velilla-Alonso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s","family":"Garc\u00eda-Pastor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngela","family":"Rodr\u00edguez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"G\u00f3mez-Rold\u00f3s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"S\u00e1nchez-Soblechero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Amaya-Pascasio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"D\u00edaz-Otero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda","family":"Fern\u00e1ndez-Bullido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Mar\u00eda","family":"Iglesias-Mohedano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"V\u00e1zquez-Al\u00e9n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Vales-Montero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio-Carmelo","family":"Gil-N\u00fa\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrleng.2020.04.007"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.es.2020.25.3.2000045"},{"key":"ref3"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030329"},{"key":"ref5"},{"key":"ref6"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030395"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2020-016299"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030225"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000507666"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030105"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-10200-2"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/514140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/514140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:21:19Z","timestamp":1745425279000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000514140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":12,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,5,27]]},"published-print":{"date-parts":[[2021,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000514140","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"value":"1015-9770","type":"print"},{"value":"1421-9786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}