{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:20:26Z","timestamp":1790742026730,"version":"4.1.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>The coexistence of hidradenitis suppurativa (HS) and acne fulminans (AF) has only recently been reported in the literature. We present a case of a 17-year-old man who presented with a 2 years history of severe acne and HS. He was initially started on oral clindamycin and rifampicin for 3 months with no clinical improvement. Acne lesions became worse with the presence of nodules and necrotic ulcers, while weight loss, low-grade fever, back and knee pain, and psychological distress were noted. We prescribed adalimumab in its standard dosing regimen. Remission of AF was achieved in 3 months, whereas adalimumab has not been as effective in treating the HS lesions. Its dosage was increased to 80 mg weekly and more than 80% clinical improvement of HS lesions was obtained in 2 months. The patient maintained on this dosage till this day and efficacy is sustained. TNF-\u03b1 inhibitors are considered an effective option in the treatment of HS, while it has been also suggested as a treatment option in AF. Our patient was successfully treated with adalimumab. Since the coexistence of HS and AF has a devastating emotional effect on the patient, there is an urgent need to implement therapeutic approaches. <\/jats:p>","DOI":"10.1159\/000515002","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T21:01:18Z","timestamp":1617138078000},"page":"329-332","source":"Crossref","is-referenced-by-count":11,"title":["Successful Treatment of Coexistent Acne Fulminans and Severe Hidradenitis Suppurativa with Adalimumab"],"prefix":"10.1159","volume":"7","author":[{"given":"George","family":"Kontochristopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efthymia","family":"Agiasofitou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6303-9269","authenticated-orcid":false,"given":"Eftychia","family":"Platsidaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Kapsiocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stamatios","family":"Gregoriou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Rigopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-016-9328-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.11.028"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.4103\/ijdvl.IJDVL_834_16"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2018.80709"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtauto.2020.100071"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000446812"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159\/000503606"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13842"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2019.04.001"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18003"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/515002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/515002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:29:42Z","timestamp":1745425782000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000515002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,6,29]]},"published-print":{"date-parts":[[2021,7,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000515002","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}