{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T12:55:03Z","timestamp":1788353703360,"version":"build-2803163510"},"reference-count":17,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T00:00:00Z","timestamp":1612396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T00:00:00Z","timestamp":1612396800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Res"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Purpose:<\/i><\/b> The aim of this study was to evaluate the short-term efficacy and safety of ultrasound cycloplasty (UCP) procedure in Chinese glaucoma patients. <b><i>Methods:<\/i><\/b> As a single-center, prospective, noncomparative study, 23 eyes of 23 patients suffering from glaucoma with uncontrolled intraocular pressure (IOP) \u226521 mm Hg underwent a multidose UCP treatment with the activations of 6, 8, or10 sectors. Types of glaucoma include primary open-angle glaucoma (7\/23), primary angle closure glaucoma (PACG) (9\/23), and secondary glaucoma (SG) (7\/23). A complete ophthalmic examination including intraocular pressure (IOP) measurements was performed before UCP procedure and at 1 day, 1 month, 3 months, and 6 months after the procedure. An IOP reduction of \u226520% and IOP &#x3e;5 mm Hg without increasing hypotensive medication at the follow-up visit was defined as therapeutic success. The postoperative complications were also recorded and compared to baseline for safety evaluation. <b><i>Results:<\/i><\/b> The mean baseline IOP of 23 treated eyes was 37.2 \u00b1 12.1 mm Hg. The IOP reduction after UCP procedure was 23, 49, 33, and 34% at 1 day, 1 month, 3 months, and 6 months, respectively. Thus, the corresponding overall therapeutic success rates reached 61% (14\/23), 83% (19\/23), 65% (15\/23), and 61% (14\/23), respectively. Baseline IOPs of 8- and 10-sector groups (37.0 \u00b1 9.9 mm Hg and 50.1 \u00b1 12.2 mm Hg) were significantly higher than that of 6 sector groups (30.1 \u00b1 8.2 mm Hg). Therapeutic success rates of 6-, 8-, and 10-sector groups reached 44% (4\/9), 56% (5\/9), and 100% (5\/5), respectively. There were the highest percentage of IOP reduction (50 and 41%) and therapeutic success rate (6\/7; 86% and 7\/9; 78%) in the SG group and PACG group, respectively. In addition, preoperative ocular pain symptoms of 4 patients were all disappeared within 1 week after UCP. No serious intraoperative or postoperative complications occurred. <b><i>Conclusion:<\/i><\/b> UCP procedure is an effective and well-tolerated treatment to reduce IOP in Chinese glaucoma patients, which offered a novel alternative for glaucoma treatment. <\/jats:p>","DOI":"10.1159\/000515013","type":"journal-article","created":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T22:01:36Z","timestamp":1612476096000},"page":"466-473","source":"Crossref","is-referenced-by-count":13,"title":["Ultrasound Cycloplasty in Chinese Glaucoma Patients: Results of a 6-Month Prospective Clinical Study"],"prefix":"10.1159","volume":"65","author":[{"given":"Qin","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenwen","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangshuang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiping","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,2,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31469-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.50020"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-016-0333-6"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.116533"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2019.05.001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2011.01.017"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12913"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4950318"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4016536"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1024_17"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2018.02.005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000620"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-017-3817-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001497"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14973"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2014.910509"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000001400"}],"container-title":["Ophthalmic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/515013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/515013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:29:52Z","timestamp":1745425792000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000515013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,4]]},"references-count":17,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,8,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000515013","archive":["Portico"],"relation":{},"ISSN":["0030-3747","1423-0259"],"issn-type":[{"value":"0030-3747","type":"print"},{"value":"1423-0259","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,4]]}}}