{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:31:49Z","timestamp":1747193509155,"version":"3.40.5"},"reference-count":10,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ocul Oncol Pathol"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Purpose:<\/i><\/b> To report retinal function findings on the choroidal nevus. <b><i>Methods:<\/i><\/b> Prospective descriptive case series of 7 patients (<i>n<\/i> = 7 eyes) presenting a melanocytic choroidal lesion consistent with choroidal nevus and no other ocular disease. Baseline evaluation included measurement of best-corrected visual acuity (BCVA), color and near-infrared fundus pictures, and spectral-domain OCT (Heidelberg Engineering). Retinal function was tested with microperimetry (MAIA; CenterVUE, Padova) using a standard grid (\u00b5P1) and a linear grid (\u00b5P2) that distribute test points on retinal areas that overlaid the choroidal lesion as well as lesion-free areas equidistantly to the fovea in 3 parallel lines. mfERG was performed following the International Society for Clinical Electrophysiology of Vision (ISCEV) recommendation using a 61-hexyagon protocol. <b><i>Results:<\/i><\/b> BCVA was 20\/25 (0.1 logMAR) or better in all 7 eyes. Microperimetry showed central stable fixation on all eyes, with mean \u00b1 SE sensitivity threshold significantly decreased on retinal areas overlaying the lesions (\u00b5P1): 21.8 \u00b1 0.6 dB versus 25.2 \u00b1 0.9 dB on nonaffected retinal areas (<i>p<\/i> &#x3c; 0.001). Sensitivity was also decreased on \u00b5P2: 23.7 \u00b1 0.2 dB for areas overlying the nevi and 25.7 \u00b1 0.3 dB for the nonaffected retina (<i>p<\/i> &#x3c; 0.001). mfERG responses showed no focal amplitude or implicit-time changes on the retina in the topographical region corresponding to the nevus for all patients. <b><i>Conclusion:<\/i><\/b> Our results indicate that choroidal nevi may cause significant retinal sensitivity impairment, as shown by microperimetry, but preserved mfERG response indicates that the retinal function may be only partially impaired. <\/jats:p>","DOI":"10.1159\/000515561","type":"journal-article","created":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T21:01:40Z","timestamp":1620334900000},"page":"287-293","source":"Crossref","is-referenced-by-count":0,"title":["Decreased Retinal Sensitivity Overlying Choroidal Nevi"],"prefix":"10.1159","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6931-4273","authenticated-orcid":false,"given":"Marina L.","family":"de Albuquerque","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2946-3757","authenticated-orcid":false,"given":"Zelia","family":"Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Messias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Jorge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,5,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2005.11.1254"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.08.045"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12092"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-018-0943-7"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4103\/0974-620X.192288"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_536_18"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31812565d2"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3928\/23258160-20180501-10"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(03)00868-7"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2016.3633"}],"container-title":["Ocular Oncology and Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/515561","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/515561","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:35:46Z","timestamp":1745426146000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000515561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,9,2]]},"published-print":{"date-parts":[[2021,9,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000515561","archive":["Portico"],"relation":{},"ISSN":["2296-4681","2296-4657"],"issn-type":[{"type":"print","value":"2296-4681"},{"type":"electronic","value":"2296-4657"}],"subject":[],"published":{"date-parts":[[2021]]}}}