{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:28:27Z","timestamp":1745468907033,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ. &lt;b&gt;&lt;i&gt;Case Presentation:&lt;\/i&gt;&lt;\/b&gt; Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis. &lt;b&gt;&lt;i&gt;Discussion:&lt;\/i&gt;&lt;\/b&gt; Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth. <\/jats:p>","DOI":"10.1159\/000516300","type":"journal-article","created":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T21:03:45Z","timestamp":1623272625000},"page":"408-412","source":"Crossref","is-referenced-by-count":2,"title":["Hair Growth in a Patient with Alopecia Areata on Tocilizumab"],"prefix":"10.1159","volume":"7","author":[{"given":"Chloe J.","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly E.","family":"Flanagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James T.","family":"Pathoulas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Pupo Wiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryanne M.","family":"Senna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,6,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.04.031"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.06.029"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.06.010"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.05.002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.08.019"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-5890(02)00210-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/ar1917"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2013.07.002"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/omcr\/omw027"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5693572"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s1359-6101(02)00027-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2007.00643.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.274"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.116731"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3645"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/exd.14155"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/516300","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/516300","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:43:21Z","timestamp":1745426601000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000516300"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,8,31]]},"published-print":{"date-parts":[[2021,10,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000516300","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"type":"print","value":"2296-9195"},{"type":"electronic","value":"2296-9160"}],"subject":[],"published":{"date-parts":[[2021]]}}}