{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:03:59Z","timestamp":1769126639122,"version":"3.49.0"},"reference-count":5,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>The mechanism of alopecia areata (AA) is not well-elucidated, and hair follicle melanogenesis pathways are implicated as possible sources for autoantigens. After a retrospective medical record review at a single tertiary medical center, the hair color of 112 AA patients were identified and compared to a control group of 104 androgenetic alopecia patients. There were no statistically significant differences in the natural hair color prevalence between the 2 groups (&lt;i&gt;p&lt;\/i&gt; = 0.164), and hair color was not a predictor of the alopecia type. Our results suggest hair pigmentation, determined by the eumelanin-to-pheomelanin ratio, is not a positive risk factor for AA development. We hope that our study will encourage multiple large-scale, collaborative, retrospective medical reviews to determine if our results are reproducible in diverse patient populations. <\/jats:p>","DOI":"10.1159\/000516301","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T21:00:45Z","timestamp":1622754045000},"page":"370-372","source":"Crossref","is-referenced-by-count":4,"title":["Hair Follicle Melanogenesis Reflected in Hair Pigmentation as a Developmental Factor in Alopecia Areata"],"prefix":"10.1159","volume":"7","author":[{"given":"Margit","family":"Juhasz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalynn R.Z.","family":"Conic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Atanaskova Mesinkovska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,6,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5114\/pdia.2014.40956"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.017"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000375"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12264"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.114705"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/516301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/516301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:43:22Z","timestamp":1745426602000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000516301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":5,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,8,31]]},"published-print":{"date-parts":[[2021,10,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000516301","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}