{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:43:57Z","timestamp":1790775837494,"version":"4.1.0"},"reference-count":24,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Transcutaneous bilirubin (TcB) measurement offers a noninvasive approach for bilirubin screening; however, its accuracy in preterm infants is unclear. This study determined the agreement between TcB and total serum bilirubin (TSB) among preterm infants. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A multisite prospective cohort study was conducted at 3 NICUs in Ontario, Canada, September 2016 to June 2018. Among 296 preterm infants born at 24&lt;sup&gt;0\/7&lt;\/sup&gt; to 35&lt;sup&gt;6\/7&lt;\/sup&gt; weeks, 856 TcB levels were taken at the forehead, sternum, and before and after the initiation of phototherapy with TSB measurements. Bland-Altman plots and 95% limits of agreement (LOA) expressed agreement between TcB and TSB. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The overall mean TcB-TSB difference was \u221224.5 \u03bcmol\/L (95% LOA \u2212103.3 to 54.3), 1.6 \u03bcmol\/L (95% LOA \u221273.4 to 76.5) before phototherapy, and \u221231.1 \u03bcmol\/L (95% LOA \u2212105.5 to 43.4) after the initiation of phototherapy. The overall mean TcB-TSB difference was \u221215.2 \u03bcmol\/L (95% LOA \u221286.8 to 56.3) at the forehead and \u221224.4 \u03bcmol\/L (95% LOA \u2212112.9 to 64.0) at the sternum. The mean TcB-TSB difference was \u221231.4 \u03bcmol\/L (95% LOA \u221295.3 to 32.4) among infants born 24\u201328 weeks, \u221225.5 \u03bcmol\/L (95% LOA \u2212102.7 to 51.8) at 29\u201332 weeks, and \u221215.9 \u03bcmol\/L (95% LOA \u2212107.4 to 75.6) at 33\u201335 weeks. Measures did not differ by maternal ethnicity. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Among preterm infants, TcB may offer a noninvasive, immediate approach to screening for hyperbilirubinemia with more careful use in preterm infants born at &amp;#x3c;33 weeks\u2019 gestation, as TcB approaches treatment thresholds. Its underestimation of TSB after the initiation of phototherapy warrants the use of TSB for clinical decision-making after the initiation of phototherapy. <\/jats:p>","DOI":"10.1159\/000516648","type":"journal-article","created":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T21:00:32Z","timestamp":1623963632000},"page":"443-453","source":"Crossref","is-referenced-by-count":19,"title":["Transcutaneous versus Total Serum Bilirubin Measurements in Preterm Infants"],"prefix":"10.1159","volume":"118","author":[{"given":"Thivia","family":"Jegathesan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas M.","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel G.","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibhuti","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin Z.","family":"Hayeems","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sgro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the NeoHBC","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.297"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.12.067"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4847.116402"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2012.71"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/bmjpo-2017-000065"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000469"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bmjpo-2020-000681"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-018-1290-9"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22267"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-018-2739-4"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218131"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0000000000000738"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1713"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/10543400701329422"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1177\/0962280211402548"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2014.05.009"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2015.34"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-013-2142-0"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-019-0557-9"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1515\/jpm-2018-0429"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159\/000505818"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1258\/acb.2009.009072"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.05.080"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1670800"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/516648","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/516648","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:57:51Z","timestamp":1745420271000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000516648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":24,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,8,19]]},"published-print":{"date-parts":[[2021,8,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000516648","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.14796306","asserted-by":"subject"}]},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}