{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:15:09Z","timestamp":1792167309883,"version":"4.4.0"},"reference-count":16,"publisher":"S. Karger AG","issue":"9-10","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> The coronavirus disease 2019 (COVID-19) is a global pandemic which may affect multiple organs and systems including testes and disrupt the gonadal functions. The current study aimed to evaluate the effect of COVID-19 on the semen parameters and sex-related hormone levels in infertile men. <b><i>Methods:<\/i><\/b> The study included 21 patients who were evaluated in Ankara City Hospital, Andrology Clinic, for male infertility and have had the diagnosis of COVID-19. All the patients were evaluated in terms of semen parameters. The follicle-stimulating hormone, luteinizing hormone, and testosterone (T) levels were also evaluated in 8 of the patients. The results were presented through 2 dependent group analyses, based on the data of the patients collected before and after the diagnosis of COVID-19. <b><i>Results:<\/i><\/b> None of the patients needed to be hospitalized at any time through the course of COVID-19. There was a significant decrease in semen volume, percentage of total motility, percentage of progressive motility, and normal sperm morphology after COVID-19 (3 [1\u20138] vs. 2.5 [1.5\u20135], <i>p<\/i> = 0.005; 48.6 \u00b1 22.1 vs. 34.7 \u00b1 20.7, <i>p<\/i> = 0.001; 35.1 \u00b1 21.7 vs. 21.8 \u00b1 15.9, <i>p<\/i> &#x3c; 0.001; 6 [3\u201324] vs. 5 [3\u201318], <i>p<\/i> = 0.015; respectively). There was also a significant decline in T level of the patients after the diagnosis of COVID-19 (350.1 \u00b1 115.5 vs. 289.8 \u00b1 103.3, <i>p<\/i> = 0.009). <b><i>Conclusion:<\/i><\/b> COVID-19 may have unfavorable effects on the gonadal functions and may lead to further deterioration of the semen parameters in infertile men, which should be considered through the evaluation for infertility. <\/jats:p>","DOI":"10.1159\/000517276","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T21:00:35Z","timestamp":1626382835000},"page":"743-748","source":"Crossref","is-referenced-by-count":60,"title":["Does COVID-19 Worsen the Semen Parameters? Early Results of a Tertiary Healthcare Center"],"prefix":"10.1159","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3439-2105","authenticated-orcid":false,"given":"Erdem","family":"Ko\u00e7","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bu\u011fra Bilge","family":"Kesero\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,7,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0968-3"},{"key":"ref2"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2020.05.009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.052"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000510531"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000511616"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159\/000511618"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000511617"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040920"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2020.05.028"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/and.12026"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.105.044776"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2014.02.012"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.1180"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S241099"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517276","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:03:19Z","timestamp":1745420599000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000517276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":16,"journal-issue":{"issue":"9-10","published-online":{"date-parts":[[2021,9,1]]},"published-print":{"date-parts":[[2021,9,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000517276","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}