{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:26:43Z","timestamp":1791581203262,"version":"4.3.4"},"reference-count":22,"publisher":"S. Karger AG","issue":"8","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> This study investigated whether fetal growth deceleration in term, appropriate-for-gestational-age (AGA) fetuses is associated with placental insufficiency and nonreassuring fetal heart rate (NRFHR) at birth. <b><i>Methods:<\/i><\/b> In this prospective study, 246 low-risk, singleton pregnancies at term with AGA fetuses were recruited. Correlation between decreased growth velocity (decline in estimated fetal weight [EFW] percentile), low EFW (EFW<sup>Q1<\/sup> = latest EFW between 11 and 25% percentiles), umbilical artery (UA) pulsatility index (PI), middle cerebral artery (MCA) PI, and cerebro-placental ratio (CPR) with cesarean and instrumental deliveries due to NRFHR were tested. <b><i>Results:<\/i><\/b> The median change between fetal weight estimates (percentiles\/week) was +0.49% (95% CI: \u22124 to +5%). Ten percent had decreased EFW percentile &#x3e;3.5%\/week. Fetal growth velocity\/week was associated with MCA (<i>r<\/i> = 0.21, <i>p<\/i> &#x3c; 0.001) and CPR (<i>r<\/i> = 0.24, <i>p<\/i> &#x3c; 0.001) and inversely correlated with UA PI (<i>r<\/i> = \u22120.28, <i>p<\/i> &#x3c; 0.001). NRFHR and cesarean section (CS) rates due to NRFHR were associated with decreased growth velocity, EFW<sup>Q1<\/sup>, and low CPR. The combination of abnormal CPR with decreased growth velocity occurred in 12 pregnancies, of which 5 (42%) had urgent CS due to NRFHR. The combination of abnormal CPR with EFW<sup>Q1<\/sup> occurred in 9 pregnancies, of which 4 (44%) had urgent CS due to NRFHR. These combinations increased the likelihood ratio of CS due to NRFHR two-fold (8.41; 2.54\u201324.5) but did not significantly alter the number needed to treat by elective CS (3.78\u20134.68). <b><i>Conclusion:<\/i><\/b> Fetal growth velocity, EFW between 10 and 25th percentiles (EFW<sup>Q1<\/sup>), and abnormal CPR improves prediction of unplanned CS due to NRFHR among term AGA fetuses. This should be considered when counseling about the delivery method. <\/jats:p>","DOI":"10.1159\/000517519","type":"journal-article","created":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T21:00:32Z","timestamp":1630443632000},"page":"624-632","source":"Crossref","is-referenced-by-count":6,"title":["Growth Velocity and Doppler Evaluation to Predict Nonreassuring Fetal Heart Rate at Birth in Low-Risk Women: A Prospective, Longitudinal Study"],"prefix":"10.1159","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5224-0813","authenticated-orcid":false,"given":"Hanoch","family":"Schreiber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hen","family":"Toledano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tal","family":"Weissbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Kassif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Tsur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tal","family":"Biron-Shental","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boaz","family":"Weisz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,8,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f108"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2007.00742.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62233-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.01.022"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2010.041"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.05.008"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.12.210"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1684470"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2019.06.026"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15884"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.03.002"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142788"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-017-0928-z"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15884"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.09.019"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7738"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.12.003"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.02.005"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0000000000000490"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14842"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/s1550-8579(07)80004-0"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517519","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517519","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:06:07Z","timestamp":1745420767000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000517519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":22,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,10,22]]},"published-print":{"date-parts":[[2021,10,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000517519","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}