{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:37:37Z","timestamp":1790120257154,"version":"4.0.1"},"reference-count":17,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Introduction:<\/i><\/b> Mild cognitive impairment (MCI) represents a target for early detection and intervention in dementia, yet there is a shortage of validated screening tools in Arabic to diagnose MCI. The mini-Addenbrooke\u2019s Cognitive Examination (m-ACE) is a brief cognitive battery that is scored out of 30 and can be administered in under 5 min providing a quick screening tool for assessment of cognition. <b><i>Objective:<\/i><\/b> We aimed to validate the m-ACE in Arabic speakers in Egypt with MCI to provide cut-off scores. <b><i>Methods:<\/i><\/b> We included 24 patients with MCI and 52 controls and administered the Arabic version of the m-ACE. <b><i>Results:<\/i><\/b> There was a statistically significant difference (<i>p<\/i> &#x3c; 0.0001) on the total m-ACE score between MCI patients (mean 18.54, SD 3.05) and controls (mean 24.54, SD 2.68). There was also a statistically significant difference between MCI patients and controls on the total score and the fluency, visuospatial, and memory recall sub-scores of the m-ACE (<i>p<\/i> &#x3c; 0.05). Performance on the m-ACE significantly correlated with both the Mini-Mental State Examination (MMSE) and the Addenbrooke\u2019s Cognitive Examination-III (ACE-III). Using a receiver operator characteristic curve, the optimal cut-off score for MCI on the m-ACE total score was 21 out of 30 (87.5% sensitivity, 84.6% specificity, and 85.5% accuracy). <b><i>Conclusions:<\/i><\/b> We validated the Arabic m-ACE in Egyptian patients with MCI and provided objective validation of it as a screening tool for MCI, with good sensitivity, specificity, and accuracy that is comparable to other translated versions of the m-ACE in MCI. <\/jats:p>","DOI":"10.1159\/000517580","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T21:01:05Z","timestamp":1626987665000},"page":"178-182","source":"Crossref","is-referenced-by-count":6,"title":["Validation of the Mini-Addenbrooke\u2019s Cognitive Examination in Mild Cognitive Impairment in Arabic Speakers"],"prefix":"10.1159","volume":"50","author":[{"given":"Tarik","family":"Qassem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"Khater","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer","family":"Emara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doha","family":"Rasheedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba M.","family":"Tawfik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed S.","family":"Mohammedin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad F.","family":"Tolba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Aly El-Gabry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Abdel Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba G.","family":"Saber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,7,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2004.01388.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.892542"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000366040"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159\/000351671"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/gps.4258"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12417"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0891988719841726"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12480"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1590\/1980-57642018dn12-040005"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617720000314"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2018.06.003"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.56.3.303"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.43.11.2412-a"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/01.xme.0000457267.05731.0f"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1963.03060120024016"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/9.3_part_1.179"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1590\/1516-4446-2012-3503"}],"container-title":["Dementia and Geriatric Cognitive Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517580","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517580","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:06:47Z","timestamp":1745420807000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000517580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":17,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,8,19]]},"published-print":{"date-parts":[[2021,8,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000517580","archive":["Portico"],"relation":{},"ISSN":["1420-8008","1421-9824"],"issn-type":[{"value":"1420-8008","type":"print"},{"value":"1421-9824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}