{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T15:58:38Z","timestamp":1782835118898,"version":"3.54.5"},"reference-count":13,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; The aim of the study was to ascertain the effect of nasal polyposis on cardiac functions. &lt;b&gt;&lt;i&gt;Material and Methods:&lt;\/i&gt;&lt;\/b&gt; A prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital. Thirty-one patients with chronic rhinosinusitis with nasal polyposis were enrolled and administered fluticasone furoate nasal spray for 3 weeks before randomly segregation into surgical or medical group. The treatment continued for 3 months in both groups. The SNOT-22 (Sino-Nasal Outcome Test-22) score, polyp grade, and right ventricular and pulmonary arterial functions were recorded in both groups before and after 3 months of the intervention. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Both groups had significant improvement in SNOT-22 scores after 3 months of intervention. Both groups showed improvement in cardiac functions, but statistical significance was found only in subjects who underwent surgery. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Nasal polyp affects cardiac functions, and this needs further evaluation and research through studies on large samples. <\/jats:p>","DOI":"10.1159\/000517976","type":"journal-article","created":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T21:00:31Z","timestamp":1624482031000},"page":"522-526","source":"Crossref","is-referenced-by-count":5,"title":["Nasal Polyposis and Its Association with Cardiac Functions"],"prefix":"10.1159","volume":"30","author":[{"given":"Sapna","family":"Dhiman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Dhiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh K.","family":"Azad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash C.","family":"Negi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhushan","family":"Lal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2311-0571","authenticated-orcid":false,"given":"Jagdeep S.","family":"Thakur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,6,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116009129"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318207f430"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006991.pub2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006549.pub2"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3950"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2500\/105065893782172240"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2016.03.020"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-5876(01)00500-6"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/194589240401800407"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22651"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2016.03.020"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.12.1144"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.2.179"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517976","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/517976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:09:58Z","timestamp":1745420998000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000517976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":13,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,12,16]]},"published-print":{"date-parts":[[2022,1,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000517976","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}