{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T01:36:57Z","timestamp":1789004217975,"version":"build-2803163510"},"reference-count":11,"publisher":"S. Karger AG","issue":"7","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>The mortality of septic shock remains high [Ann Intensive Care. 2017;7:19], so apart from usual therapy based on source control and antibiotics, some patients may need rescue therapies. Blood purification systems may play a role by facilitating the nonspecific removal of inflammatory mediators and microbiological toxins. There are different hemoadsorption systems, we describe in this case report the sequential use of Polymyxin B (PMX) endotoxin-adsorbing column (Toraymixin PMX-20R; Toray, Tokyo, Japan) and Cytosorb\u00ae (Cytosorbents Corp., New Jersey, USA). <\/jats:p>","DOI":"10.1159\/000518229","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T21:00:33Z","timestamp":1631048433000},"page":"630-633","source":"Crossref","is-referenced-by-count":15,"title":["Endotoxin and Cytokine Sequential Hemoadsorption in Septic Shock and Multi-Organ Failure"],"prefix":"10.1159","volume":"51","author":[{"given":"Juan Carlos","family":"Ruiz-Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Chiscano-Cam\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Palmada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolf","family":"Ruiz-Sanmartin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"P\u00e9rez-Carrasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nieves","family":"Larrosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Jos\u00e9","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Hern\u00e1ndez-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricard","family":"Ferrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,9,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000492379"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4683-6"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000339789"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1086\/315093"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-017-0639-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2012.12.011"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.14618"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s40635-018-0177-2"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2019.02.007"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000063108"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000371754"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/518229","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/518229","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:12:45Z","timestamp":1745421165000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000518229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,7]]},"references-count":11,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7,7]]},"published-print":{"date-parts":[[2022,7,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000518229","archive":["Portico"],"relation":{},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"value":"0253-5068","type":"print"},{"value":"1421-9735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,7]]}}}