{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:57:58Z","timestamp":1765486678193,"version":"build-2065373602"},"reference-count":22,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2021]]},"abstract":"<b><i>Objective:<\/i><\/b> We aimed to investigate the presence and severity of depressive symptoms among coronavirus disease 2019 (COVID-19) inpatients and any possible changes after their discharge. <b><i>Subject and Methods:<\/i><\/b> We collected data of patients admitted to the Infectious Disease Unit in Sassari, Italy, for COVID-19, from March 8 to May 8, 2020. The Beck Depression Inventory-II (BDI-II) was performed 1 week after admission (T0) and 1 week after discharge (T1). The cutoff point chosen to define the clinical significance of depressive symptoms was 20 (at least moderate). <b><i>Results:<\/i><\/b> Forty-eight subjects were included. Mean age was 64.3 \u00b1 17.6 years, and 32 (66.7%) were male. Most frequent comorbidities were cardiovascular diseases (19; 39.6%) and hypertension (17; 35.4%). When performing BDI-II at T0, 21 (43.7%) patients reported depressive symptoms at T0, according to the chosen cutoff point (BDI-II = 20). Eight (16.7%) patients had minimal symptoms. Mild mood disturbance and moderate and severe depressive symptoms were found in 24 (50%), 14 (29.2%), and 2 (4.2%) patients, respectively, at T0. The comparison of the BDI-II questionnaire at T0 with T1 showed a significant improvement in the total score (<i>p<\/i> &#x3c; 0.0001), as well as in 4 out of the 5 selected questions of interest (<i>p<\/i> &#x3c; 0.05). Univariate analysis showed that kidney failure and the death of a roommate were significantly associated with severity of mood disorders. <b><i>Conclusion:<\/i><\/b> Mood disturbances and depressive symptoms commonly occur among COVID-19 inpatients. Our results show that COVID-19 inpatients might be at higher risk for developing depressive reactive disorders and could benefit from an early psychological evaluation and strategies improving sleep quality. <\/jats:p>","DOI":"10.1159\/000518490","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T21:01:39Z","timestamp":1632862899000},"page":"535-541","source":"Crossref","is-referenced-by-count":11,"title":["Mood Reactive Disorders among COVID-19 Inpatients: Experience from a Monocentric Cohort"],"prefix":"10.1159","volume":"30","author":[{"given":"Vito","family":"Fiore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8265-5400","authenticated-orcid":false,"given":"Andrea","family":"De Vito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Fanelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Geremia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elija","family":"Princic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Nivoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Maida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana","family":"Lorettu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giordano","family":"Madeddu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Babudieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_202007_22291"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/ipc.0000000000000952"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0248009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_202101_24424"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1191\/026921500676724210"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1191\/1352458503ms921oa"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2018.05.023"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-030371"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2019.02.006"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1037\/a0023632"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-020-08986-x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0190-z"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2020.07.037"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2020.05.037"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.200465"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14506"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.113134"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291718000624"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijchp.2020.07.007"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2020.02.004"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2015.12.018"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.12890\/2020_001651"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/518490","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/518490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:16:22Z","timestamp":1745421382000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000518490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":22,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,12,16]]},"published-print":{"date-parts":[[2022,1,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000518490","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"type":"print","value":"1011-7571"},{"type":"electronic","value":"1423-0151"}],"subject":[],"published":{"date-parts":[[2021]]}}}