{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:31:44Z","timestamp":1747193504788,"version":"3.40.5"},"reference-count":10,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T00:00:00Z","timestamp":1640563200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T00:00:00Z","timestamp":1640563200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Introduction:<\/i><\/b> The incidence of cancers in New York State (NYS) before and after 9\/11 including lung, colorectal, and renal cancers has been previously described. To date, the incidence of head and neck cancers (HNCs) before and after 9\/11 has not been described. <b><i>Methods:<\/i><\/b> Cancers involving the oral cavity and oropharynx; the nose, nasal cavity, nasopharynx, and middle ear; larynx; and thyroid were identified using the New York State Cancer Registry (NYSCR). Age-adjusted incidence and rates per 100,000 residents from 1987 to 2015 were analyzed using joinpoint regression. Trends in incidence using annual percent changes are presented. <b><i>Results:<\/i><\/b> The overall rate of HNC increased slightly by 0.7% (<i>p<\/i> &#x3c; 0.001) from 1987 to 2003 in NYS. From 2003 to 2008, the rate increased by 5.73% (<i>p<\/i> &#x3c; 0.001), and from 2008 to 2015, the rate increased by 1.68% (<i>p<\/i> &#x3c; 0.001). The rate of thyroid cancer increased by 6.79% (<i>p<\/i> &#x3c; 0.001) from 1987 to 2003, by 9.99% (<i>p<\/i> &#x3c; 0.001) from 2003 to 2009, and by 2.41% (<i>p<\/i> = 0.001) from 2009 to 2015. The rate of thyroid cancer was higher in women at all time points. In a subset analysis of HNCs excluding thyroid cancer, the rate decreased by 2.02% (<i>p<\/i> &#x3c; 0.001) from 1991 to 2001, followed by a nonsignificant increase of 0.1% (<i>p<\/i> = 0.515) from 2001 to 2015. The rate of oropharyngeal (OP) cancer significantly increased from 1999 to 2015 (2.65%; <i>p<\/i> &#x3c; 0.001). The rate of oral cavity cancer significantly decreased from 1987 to 2003 (1.97%; <i>p<\/i> &#x3c; 0.001), with no significant change after 2003. The rate of laryngeal cancer decreased significantly by 2.43% (<i>p<\/i> &#x3c; 0.001) from 1987 to 2015, as did the rate of nasal cavity\/nasopharyngeal cancer (0.33%; <i>p<\/i> = 0.03). <b><i>Conclusions:<\/i><\/b> In NYS, OP cancer and thyroid cancer rates increased significantly during the study period. The rate of thyroid cancer was higher in women. The rate of combined HNC increased significantly after 9\/11 compared to before 9\/11; however, in a subset analysis of all HNC patients excluding thyroid cancer, the rate decreased significantly prior to 9\/11 and then nonsignificantly increased afterward. This suggests that the increase in thyroid cancer accounts for the increase in combined HNC in NYS. The impact of 9\/11 on rates of HNC requires further research. <\/jats:p>","DOI":"10.1159\/000519840","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T22:00:35Z","timestamp":1640642435000},"page":"324-335","source":"Crossref","is-referenced-by-count":1,"title":["Incidence of Head and Neck Cancers before and after 9\/11 in New York City and New York State"],"prefix":"10.1159","volume":"84","author":[{"given":"Rosalie","family":"Machado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5928-762X","authenticated-orcid":false,"given":"Tristan","family":"Tham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6569-9623","authenticated-orcid":false,"given":"Daniel","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hiltzik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ansley","family":"Roche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,12,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.0504"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097-0258(20000215)19:3<335::aid-sim336>3.0.co;2-z"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2017.05.008"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2015.03.001"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.2719"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.7906"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.7910"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16071258"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66698-6"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/srep36305"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/519840","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/519840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:29:09Z","timestamp":1745422149000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000519840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,27]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,7,18]]},"published-print":{"date-parts":[[2022,7,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000519840","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"type":"print","value":"0301-1569"},{"type":"electronic","value":"1423-0275"}],"subject":[],"published":{"date-parts":[[2021,12,27]]}}}