{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:15:58Z","timestamp":1782458158502,"version":"3.54.5"},"reference-count":37,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["GE Port J Gastroenterol"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Lifestyle changes are the mainstay treatment of nonalcoholic fatty liver disease (NAFLD). We aimed to assess the magnitude of weight loss in a group of NAFLD patients followed on a combined lifestyle intervention by a multidisciplinary team. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Patients were assessed before and after a 12-month dietary intervention (Mediterranean diet aiming at weight loss). Patients who received a structured dietary plan along with general lifestyle recommendations were designated as the multidisciplinary treatment (MdT) group. Patients who declined follow-up still received general lifestyle recommendations and were designated as the conventional treatment group, being used as a control group. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; From the 77 patients with documented NAFLD, 31.2% of patients were overweight and 55.8% obese; 66 patients constituted the MdT group and 11 the conventional treatment group. After 3 months, 89% of patients lost weight; at 6 months, 75.4% maintained the weight lost. At 12 months, 65% of patients still decreased their weight, with 92.2% of patients in the MdT group still maintaining a lower weight than baseline versus just 50% in the conventional group (&lt;i&gt;p&lt;\/i&gt; = 0.008). Only patients in the MdT group presented a weight loss higher than 10% (9.6%; &lt;i&gt;n&lt;\/i&gt; = 6). At 12 months patients in the MdT group presented an average reduction of 4.2 kg versus a reduction of just 0.6 kg in the conventional treatment group (&lt;i&gt;p&lt;\/i&gt; = 0.016). The MdT group, but not the conventional group, presented significant differences in liver enzymes at 12 months compared to baseline. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Adherence to a multidisciplinary approach, compared to management solely by a hepatologist, in NAFLD patients, is effective with greater weight loss after a 12-month follow-up and a lower rate of weight gain recurrence. <\/jats:p>","DOI":"10.1159\/000519932","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T22:00:48Z","timestamp":1638396048000},"page":"401-408","source":"Crossref","is-referenced-by-count":6,"title":["NAFLD Nutritional Management: Results from a Multidisciplinary Approach"],"prefix":"10.1159","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8594-1720","authenticated-orcid":false,"given":"Sara\u00a0Raquel\u00a0Os\u00f3rio","family":"Policarpo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana\u00a0V.","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Barreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8537-8744","authenticated-orcid":false,"given":"Helena","family":"Cortez-Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,12,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28431"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.05.036"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12407"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32511-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2015.08.004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2018.1503947"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/nu11030677"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.05.016"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/nu13051442"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.11.004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009825.pub2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2013.08.014"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00020-0"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.01.029"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21496"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21178"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.06.022"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043134"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.2014-0256"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.7762\/cnr.2015.4.4.250"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2009.09.001"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3390\/nu10020157"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665113000013"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14818"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3390\/nu12123860"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3390\/nu13030966"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2021.100256"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13435"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-019-00475-2"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3390\/nu12061674"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1017\/s0007114521002270"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.04.011"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-021-07052-9"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.04.005"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154203"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114521001100"}],"container-title":["GE - 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