{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:42:38Z","timestamp":1791852158830,"version":"4.3.4"},"reference-count":28,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2022]]},"abstract":"Invasive candidiasis is predominantly seen in immunosuppressed patients and carries a significant mortality. The clinical spectrum of invasive candidiasis encompasses candidemia and disseminated infection (intra-abdominal abscess, osteomyelitis, endophthalmitis, and <i>Candida<\/i> meningitis). The existence of <i>Candida<\/i> pneumonia has been largely debated over the years due to its rarity and presence of frequent colonization. Demonstration of <i>Candida<\/i> species by lung biopsy along with evidence of inflammation is the only way to confirm this entity. The interpretation of <i>Candida<\/i> in respiratory specimens and the decision to initiate antifungal therapy is controversial due to the lack of clinical evidence. In this mini-review, we discuss the currently available clinical data from the literature on <i>Candida<\/i> pneumonia and future perspectives regarding the need for antifungal therapy in such patients.<\/jats:p>","DOI":"10.1159\/000520111","type":"journal-article","created":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T17:31:44Z","timestamp":1634059904000},"page":"98-102","source":"Crossref","is-referenced-by-count":42,"title":["<b><i>Candida<\/i><\/b> Pneumonia: An Innocent Bystander or a Silent Killer?"],"prefix":"10.1159","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9524-5278","authenticated-orcid":false,"given":"Durga Shankar","family":"Meena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2014.02.006"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1086\/432060"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3201\/eid1710.110087"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.26"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.59.030804.121034"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90546-0"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199305000-00001"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofu026"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.156.2.9612023"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1482-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155033"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/jof6010026"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009650"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-016-0032-5"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2016.3892"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-0065-6"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.09.002"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s40560-015-0097-0"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.41.12.5645-5649.2003"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31828a25d6"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/827692"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02180-15"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1186\/s41479-021-00090-x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftx029"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000886"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.10.44"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1186\/cc10276"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-014-3352-2"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/520111","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/520111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T11:26:31Z","timestamp":1745407591000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000520111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,12]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,3,11]]},"published-print":{"date-parts":[[2022,3,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000520111","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,12]]}}}