{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T04:07:39Z","timestamp":1749442059116,"version":"3.40.5"},"reference-count":36,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Res"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Introduction:<\/i><\/b> This study aimed to investigate the relationship between the choroidal circulation and glaucoma, assessing macular choroidal thickness (MCT) as a predictive value of glaucomatous visual field damage. <b><i>Methods:<\/i><\/b> Twenty primary open-angle glaucoma patients were recruited. Patients underwent 2 SS-OCT scans: one with DRI OCT (Topcon) and the other with PLEX Elite 9000 (Zeiss). Standard OCT parameters were acquired by DRI OCT, while MCT was manually measured in 5 points on Plex ELITE 9000 images. The relationship among MCT, standard OCT parameters, and visual field indices was evaluated. Pearson\u2019s <i>r<\/i> correlation was calculated to evaluate these relationships. Reproducibility of measurements was analyzed. <b><i>Results:<\/i><\/b> MCT measurements showed a good intra- and interobserver repeatability. A negative correlation appeared between MCT and BMI (<i>r<\/i> = \u22120.518, <i>p<\/i> = 0.023). Mean deviation showed a statistically significant correlation with MCT measured at subfoveal and at 1,000 \u03bcm nasally (<i>r<\/i> = 0.50, <i>p<\/i> = 0.03, and <i>r<\/i> = 0.52, <i>p<\/i> = 0.023). A correlation was found between the 2 MCT (Zeiss vs. Topcon) measurements and between MCT and peripapillary choroidal thickness (<i>r<\/i> = 0.944 and <i>r<\/i> = 0.740, <i>p<\/i> &#x3c; 0.001, respectively). <b><i>Conclusions:<\/i><\/b> A good intra- and interobserver reproducibility was found. MCT showed a weak predictive value of glaucomatous visual field damage. A significant correlation was found between MCT and BMI. <\/jats:p>","DOI":"10.1159\/000520834","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T22:00:41Z","timestamp":1637618441000},"page":"417-424","source":"Crossref","is-referenced-by-count":2,"title":["Macular Choroidal Thickness: Evaluation of Variability among Measurements and Assessment of Predictive Value of Glaucomatous Visual Field Damage"],"prefix":"10.1159","volume":"65","author":[{"given":"Maria","family":"Marenco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Rissotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Palamini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2433-0704","authenticated-orcid":false,"given":"Carlo 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Enrico","family":"Traverso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0524-2637","authenticated-orcid":false,"given":"Michele","family":"Iester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.10.1268"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00159262"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000310179"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-9566"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000275"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199702000-00006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.77.7.430"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1964.00970010235017"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/s0042-6989(02)00022-6"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-10483"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.05.032"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.08.030"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.12.008"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4383"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0109683"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-10388"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6600"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.07.011"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2011.01.002"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-013-0290-4"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-12-29"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000045"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.05.037"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2012.02762.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000166"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-18570"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.3192"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6377"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-13868"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-016-0227-z"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110265"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.18240\/ijo.2019.04.13"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000926"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157333"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0189376"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1159\/000508253"}],"container-title":["Ophthalmic 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