{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:07:46Z","timestamp":1790705266413,"version":"4.1.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Introduction:<\/i><\/b> Patients undergoing weight loss surgery do not improve their aerobic capacity or peak oxygen uptake (VO<sub>2<\/sub>peak) after bariatric surgery and some still complain about asthenia and\/or breathlessness. We investigated the hypothesis that a post-surgery muscular limitation could impact the ventilatory response to exercise by evaluating the post-surgery changes in muscle mass, strength, and muscular aerobic capacity, measured by the first ventilatory threshold (VT). <b><i>Methods:<\/i><\/b> Thirteen patients with obesity were referred to our university exercise laboratory before and 6 months after bariatric surgery and were matched by sex, age, and height to healthy subjects with normal weight. All subjects underwent a clinical examination, blood sampling, and body composition assessment by dual-energy X-ray absorptiometry, respiratory and limb muscle strength assessments, and cardiopulmonary exercise testing on a cyclo-ergometer. <b><i>Results:<\/i><\/b> Bariatric surgery resulted in a loss of 34% fat mass, 43% visceral adipose tissue, and 12% lean mass (LM) (<i>p<\/i> &#x3c; 0.001). Absolute handgrip, quadriceps, or respiratory muscle strength remained unaffected, while quadriceps\/handgrip strength relative to LM increased (<i>p<\/i> &#x3c; 0.05). Absolute VO<sub>2<\/sub>peak or VO<sub>2<\/sub>peak\/LM did not improve and the first VT was decreased after surgery (1.4 \u00b1 0.3 vs. 1.1 \u00b1 0.4 L min<sup>\u22121<\/sup>, <i>p<\/i> &#x3c; 0.05) and correlated to the exercising LM (LM legs) (<i>R<\/i> = 0.84, <i>p<\/i> &#x3c; 0.001). <b><i>Conclusions:<\/i><\/b> Although bariatric surgery has numerous beneficial effects, absolute VO<sub>2<\/sub>peak does not improve and the weight loss-induced LM reduction is associated to an altered muscular aerobic capacity, as reflected by an early VT triggering early exercise hyperventilation. <\/jats:p>","DOI":"10.1159\/000521242","type":"journal-article","created":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T22:00:36Z","timestamp":1643320836000},"page":"248-256","source":"Crossref","is-referenced-by-count":27,"title":["Lean Mass Loss and Altered Muscular Aerobic Capacity after Bariatric Surgery"],"prefix":"10.1159","volume":"15","author":[{"given":"Na","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corentin","family":"Scoubeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Forton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Loi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Closset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4505-7815","authenticated-orcid":false,"given":"Gael","family":"Deboeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Jacques","family":"Moraine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malgorzata","family":"Klass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitalie","family":"Faoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2022,1,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003641.pub4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-019-03996-0"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1381\/09608920160556715"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-012-0795-9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-199622050-00001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jshs.2016.08.004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2009.05.023"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2012.09.002"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.166.4.518"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13040"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.115.111732"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1967.22.1.71"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1113\/JP279963"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2017.09.533"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-008-9437-7"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1590\/s1413-35552012000300008"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-015-1088-2"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136944"}],"container-title":["Obesity Facts"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/521242","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/521242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:38:01Z","timestamp":1745422681000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000521242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,3,22]]},"published-print":{"date-parts":[[2022,3,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000521242","archive":["Portico"],"relation":{},"ISSN":["1662-4025","1662-4033"],"issn-type":[{"value":"1662-4025","type":"print"},{"value":"1662-4033","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}