{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T21:20:42Z","timestamp":1773436842151,"version":"3.50.1"},"reference-count":12,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; COVID-19 has varied clinical manifestations, from asymptomatic to severe cases, and conjunctivitis is one of them, but sometimes a lone initial symptom is found to be present. The aim of this study was to identify the prevalence of conjunctivitis as the first symptom in COVID-19 patients in a primary healthcare unit. &lt;b&gt;&lt;i&gt;Methodology:&lt;\/i&gt;&lt;\/b&gt; A retrospective study was conducted, analyzing the presenting complains\/symptoms and results of COVID-19-confirmatory tests. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Out of the 672 cases that were sent for RT-PCR testing, only 121 (18%) were found to be positive. Among these, 2.67% patients had both conjunctivitis and COVID-19, 77.77% patients had unilateral eye affected, while 22.22% had bilateral conjunctivitis of varying degrees. Fifteen patients diagnosed to have both acute conjunctivitis and COVID-19 presented other symptoms associated with COVID-19 infection. Three patients had only acute conjunctivitis during their entire course of COVID-19. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Conjunctivitis is a symptom of COVID-19 and may be the first sign of the infection, until the onset of the classical manifestations; such patients may continue to be a viral reservoir. Physicians should not miss unilateral conjunctivitis as it can be the only presenting complaint of COVID-19 during the initial phase, which might worsen if undetected and can aid in the spread of the contagion. <\/jats:p>","DOI":"10.1159\/000521808","type":"journal-article","created":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T22:00:31Z","timestamp":1641420031000},"page":"66-73","source":"Crossref","is-referenced-by-count":13,"title":["COVID-19 and the Human Eye: Conjunctivitis, a Lone COVID-19 Finding \u2013 A Case-Control Study"],"prefix":"10.1159","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4950-9962","authenticated-orcid":false,"given":"Valeria","family":"Mocanu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dharmesh","family":"Bhagwani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhinav","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Borza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciprian Ilie","family":"Rosca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morariu","family":"Stelian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shalini","family":"Bhagwani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Haidar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lajwanti","family":"Kshtriya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilima Rajpal","family":"Kundnani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florin-Raul","family":"Horhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raluca","family":"Horhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2022,1,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1710317"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11952"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25725"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12708"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7417\/CT.2020.2212"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2020.04.001"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-020-04641-8"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2020.e00774"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25938"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bmjophth-2020-000563"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.06.052"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_2567_20"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/521808","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/521808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:44:08Z","timestamp":1745423048000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000521808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,3,11]]},"published-print":{"date-parts":[[2022,3,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000521808","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}