{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T10:59:01Z","timestamp":1768820341355,"version":"3.49.0"},"reference-count":28,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; The literature indicates that decompression of Chiari I malformations (CM-1) may resolve symptoms of sleep apnea. This study aims to identify the incidence of obstructive sleep apnea (OSA), central sleep apnea (CSA), and mixed sleep apnea in a cohort of pediatric CM-1 patients treated at our institution. We also assessed apnea-hypopnea index and symptomatology before and after surgery to investigate if Chiari decompression is a viable treatment for sleep apnea in CM-1 patients. Improvement relative to ENT surgical intervention was also considered. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We identified 75 patients who underwent polysomnography (PSG) from our database of 465 CM-1 patients. Sleep apnea diagnosis was based on the sleep physician\u2019s overall interpretation of the PSG. Symptomatology pre- and post-surgery was analyzed. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Of the 75 CM-1 patients that underwent PSG, 23 were diagnosed with sleep apnea. Sixteen had OSA, 6 had CSA, and 1 had mixed apnea. Twelve OSA patients received ENT intervention. Eight improved and 2 further improved after Chiari decompression. Of the 4 patients that did not improve, one of those later improved following Chiari decompression. Of the 6 CSA patients, 2 underwent Chiari decompression, but only one improved. The mixed apnea patient underwent several ENT interventions that did not relieve symptoms but improved following Chiari decompression. &lt;b&gt;&lt;i&gt;Discussion\/Conclusions:&lt;\/i&gt;&lt;\/b&gt; Based on our results, sleep apnea in CM-1 patients may be obstructive, central, or mixed and is likely multifactorial. A multidisciplinary approach to the management of these patients is important, including neurosurgery, otolaryngology, and sleep medicine. Future prospective studies will lend further insight into this condition and its management. <\/jats:p>","DOI":"10.1159\/000523779","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T22:00:30Z","timestamp":1645740030000},"page":"175-183","source":"Crossref","is-referenced-by-count":6,"title":["Management of Sleep Apnea in Children with Chiari I Malformation: A Retrospective Study"],"prefix":"10.1159","volume":"57","author":[{"given":"Moira","family":"Moore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Fuell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supriya K.","family":"Jambhekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eylem","family":"Ocal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory W.","family":"Albert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2022,2,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198810000-00020"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3171\/2009.7.JNS09174"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.80.2.231"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2008.05.017"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(95)00180-n"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000191394.53786.62"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-017-3399-9"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/088307389501000116"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/s0387-7604(01)00383-7"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2015.06.009"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00282.2006"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1067\/mph.2003.36"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/pl00011947"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-010-0407-7"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-011-1500-z"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-007-0428-0"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/23.5.1f"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2017.08.001"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2013.05.025"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.085324"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2011.01.008"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199601113340207"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1996.tb15076.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1993.tb04222.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-8-15"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1136\/thx.50.6.690"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1985.132.4.929"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21294"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/523779","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/523779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:54:50Z","timestamp":1745423690000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000523779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":28,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,6,20]]},"published-print":{"date-parts":[[2022,6,28]]}},"URL":"https:\/\/doi.org\/10.1159\/000523779","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}