{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:08:01Z","timestamp":1790885281315,"version":"4.1.0"},"reference-count":21,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Cutaneous melanoma accounts for the majority of skin cancer-related deaths. Readily identifiable phenotypic characteristics and total body nevus count (TBNC) &amp;#x3e;50 are among the most important risk factors for cutaneous melanoma. Implementation of nevus self-count procedures and self-assessment of phenotypic traits as part of skin self-examination could be an excellent screening tool for identifying an at-risk target population. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; Objectives of the study were to assess the skills of a central Italian and eastern Spanish population sample to recognize their skin lesions via the submission of a self-assessment questionnaire and to explore which self-assessment questionnaire item combination best predicts the high-risk condition of TBNC &amp;#x3e;50. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Patients aged \u226518 years filled a self-assessment questionnaire, autonomously and prior to the dermatological visit. Subsequently, dermatologists performed total body skin examination and reported patients\u2019 skin lesions on a separate questionnaire. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; We reported fair to moderate patient-dermatologist agreement for skin lesion self-assessment. The item number of nevi on the back was the single questionnaire item most accurately predicting TBNC &amp;#x3e;50. The high-sensitivity and high-specificity classification and regression tree models for the prediction of TBNC &amp;#x3e;50 displayed different items combinations; the item nevus on the back was always the first and most important predictor in both our models. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Patients were partially able to provide correct estimation of their whole-body nevus self-count. The item nevi on the back seems to be the first and most important predictor of TBNC &amp;#x3e;50 across our models. Delivery of high-sensitivity and high-specificity prediction models based on our questionnaire item combination may help defining a high-risk target population. <\/jats:p>","DOI":"10.1159\/000523953","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T21:00:37Z","timestamp":1650661237000},"page":"986-995","source":"Crossref","is-referenced-by-count":5,"title":["Self-Assessment Questionnaire on Patient-Physician Concordance on Nevus Self-Count and Models Development to Predict High-Risk Phenotype &amp;#x3e;50 Nevi"],"prefix":"10.1159","volume":"238","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7246-7951","authenticated-orcid":false,"given":"Maria","family":"Mannino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Sollena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Concetta","family":"Fargnoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5237-0463","authenticated-orcid":false,"given":"Ketty","family":"Peris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3433-8707","authenticated-orcid":false,"given":"Eduardo","family":"Nagore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-016-0165-y"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.0702a01"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-0437-2_7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.5541"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.01.035"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/88.1.17"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.01.031"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.1.21"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-14-0295"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy023"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26408"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.11.108"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(94)70207-1"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26707"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21352"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a010125"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.10.014"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19981029)78:3%3c276::AID-IJC2%3e3.0.CO;2-S"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1023\/B:CACO.0000036451.39128.f6"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2018.460"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2020.0470"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/523953","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/523953","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:56:27Z","timestamp":1745423787000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000523953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":21,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,9,1]]},"published-print":{"date-parts":[[2022,9,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000523953","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.19634643","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}