{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:32:45Z","timestamp":1762353165355,"version":"3.40.5"},"reference-count":22,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmic Res"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Introduction:<\/i><\/b> The aim of this study was to compare the structure-function relationship with microperimetry and Octopus perimetry in primary open-angle glaucoma (POAG) patients with central visual field (VF) defects. <b><i>Methods:<\/i><\/b> Forty eyes of 24 patients with POAG were enrolled. Circumpapillary retinal nerve fiber layer (cpRNFL) analysis measured by spectral-domain optical coherence tomography (SD-OCT) of the superotemporal, temporal, and inferotemporal optic-nerve head sectors were related to corresponding microperimetric and Octopus VF clusters using the G2 grid-pattern with dynamic strategy, respectively. The structure-function relationships of both devices were assessed via a segmented regression, as well as linear regression across overall SD-OCT cpRNFL values and outside normative (&#x3c;1%) SD-OCT cpRNFL values. <b><i>Results:<\/i><\/b> Linear and segmented regression fits were similar with both devices. Across overall cpRNFL sectorial values, structure-function relations for the superotemporal, temporal, and inferotemporal sectors were <i>R<\/i><sup>2<\/sup> = 0.176 (<i>p<\/i> = &#x3c;0.001), <i>R<\/i><sup>2<\/sup> = 0.008 (<i>p<\/i> = 0.069), and <i>R<\/i><sup>2<\/sup> = 0.294 (<i>p<\/i> = &#x3c;0.001) for microperimetry and <i>R<\/i><sup>2<\/sup> = 0.189 (<i>p<\/i> = &#x3c;0.001), <i>R<\/i><sup>2<\/sup> = 0.020 (<i>p<\/i> = 0.002), and <i>R<\/i><sup>2<\/sup> = 0.326 (<i>p<\/i> = &#x3c;0.001) for Octopus perimetry. For corresponding values outside normative limits (&#x3c;1%), the relationships were <i>R<\/i><sup>2<\/sup> = 0.113 (<i>p<\/i> = &#x3c;0.001), <i>R<\/i><sup>2<\/sup> = 0.001 (<i>p<\/i> = 0.836), and <i>R<\/i><sup>2<\/sup> = 0.420 (<i>p<\/i> = &#x3c;0.001) for microperimetry and <i>R<\/i><sup>2<\/sup> = 0.192 (<i>p<\/i> = &#x3c;0.001), <i>R<\/i><sup>2<\/sup> = 0.002, (<i>p<\/i> = 0.336), and <i>R<\/i><sup>2<\/sup> = 0.366 (<i>p<\/i> = &#x3c;0.001) for Octopus perimetry. <b><i>Discussion\/Conclusion:<\/i><\/b> Structure-function analysis was similar for both devices. Fundus-tracking should be further evaluated in a longitudinal setting in patients affected by glaucoma. <\/jats:p>","DOI":"10.1159\/000524005","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T22:00:36Z","timestamp":1646949636000},"page":"437-445","source":"Crossref","is-referenced-by-count":3,"title":["Structure-Function Analysis of MP-3 Microperimetry versus Octopus Perimetry in Central Glaucomatous Visual Field Defects"],"prefix":"10.1159","volume":"65","author":[{"given":"Stefan","family":"Georgiev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0100-9862","authenticated-orcid":false,"given":"Stefan","family":"Palkovits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9596-4563","authenticated-orcid":false,"given":"Nino","family":"Hirnschall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2157-2203","authenticated-orcid":false,"given":"Andreas","family":"Schlatter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Leisser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Findl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2022,3,10]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1016\/j.preteyeres.2007.07.005"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1007\/BF00153928"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.1016\/s0161-6420(00)00284-0"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1016\/s0161-6420(91)32338-8"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1097\/01.opx.0000156311.49058.c8"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.3129\/i09-236"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1167\/tvst.7.1.17"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.2147\/OPTH.S131371"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.1097\/OPX.0b013e3182640c83"},{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.1016\/j.ajo.2017.12.002"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1001\/archopht.1988.01060140412043"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.1001\/jamaophthalmol.2013.7656"},{"doi-asserted-by":"publisher","key":"ref13","DOI":"10.1016\/j.preteyeres.2007.08.001"},{"doi-asserted-by":"publisher","key":"ref14","DOI":"10.1093\/biomet\/74.1.33"},{"doi-asserted-by":"publisher","key":"ref15","DOI":"10.1002\/sim.1545"},{"doi-asserted-by":"publisher","key":"ref16","DOI":"10.1080\/01621459.1988.10478639"},{"doi-asserted-by":"publisher","key":"ref17","DOI":"10.1111\/j.1755-3768.1975.tb01161.x"},{"doi-asserted-by":"publisher","key":"ref18","DOI":"10.1001\/archopht.1987.01060110090039"},{"doi-asserted-by":"publisher","key":"ref19","DOI":"10.1016\/j.survophthal.2006.12.008"},{"doi-asserted-by":"publisher","key":"ref20","DOI":"10.1097\/IJG.0000000000001599"},{"doi-asserted-by":"publisher","key":"ref21","DOI":"10.1016\/j.ophtha.2016.03.023"},{"doi-asserted-by":"publisher","key":"ref22","DOI":"10.1016\/s0039-6257(01)00299-5"}],"container-title":["Ophthalmic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524005","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:56:53Z","timestamp":1745423813000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000524005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,8,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000524005","archive":["Portico"],"relation":{},"ISSN":["0030-3747","1423-0259"],"issn-type":[{"type":"print","value":"0030-3747"},{"type":"electronic","value":"1423-0259"}],"subject":[],"published":{"date-parts":[[2022]]}}}