{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T19:38:34Z","timestamp":1773171514125,"version":"3.50.1"},"reference-count":3,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Introduction:<\/i><\/b> Identifying differences in outcome of basilar artery occlusion (BAO) between males and females may be useful in aiding clinical management. Recent studies have demonstrated widespread underrepresentation of women in acute stroke clinical trials. This international multicentre study aimed to determine sex differences in outcome after mechanical thrombectomy (MT) for patients with acute BAO. <b><i>Methods:<\/i><\/b> We performed a retrospective analysis of consecutive patients with BAO who had undergone MT in seven stroke centres across five countries (Singapore, Taiwan, United Kingdom, Sweden, and Germany), between 2015 and 2020. Primary outcome was a favourable functional outcome measured by a modified Ranking Scale (mRS) of 0\u20133 at 90 days. Secondary outcomes were mRS 0\u20133 upon discharge, mortality, symptomatic intracranial haemorrhage (sICH) and subarachnoid haemorrhage (SAH). <b><i>Results:<\/i><\/b> Among the 322 patients who underwent MT, 206 (64.0%) patients were male and 116 (36.0%) were female. Females were older than males (mean \u00b1 SD 70.9 \u00b1 14.3 years vs. 65.6 \u00b1 133.6 years; <i>p<\/i> = 0.001) and had higher rates of atrial fibrillation (38.9% vs. 24.2%; <i>p<\/i> = 0.012). Time from groin puncture to reperfusion was shorter in females than males (mean \u00b1 SD 57.2 \u00b1 37.2 min vs. 71.1 \u00b1 50.9 min; <i>p<\/i> = 0.021). Despite these differences, primary and secondary outcome measures were similar in females and males, with comparable rates of favourable 90-day mRS scores (mean \u00b1 SD 46 \u00b1 39.7 vs. 71 \u00b1 34.5; OR = 1.20; 95% confidence interval [CI] = 0.59\u20132.43; <i>p<\/i> = 0.611), favourable discharge mRS scores (mean \u00b1 SD 39 \u00b1 31.6 vs. 43 \u00b1 25.9; OR = 1.38; 95% CI = 0.69\u20132.78; <i>p<\/i> = 0.368) and in-hospital mortality (mean \u00b1 SD 30 \u00b1 25.9 vs. 47 \u00b1 22.8; OR = 1.15; 95% CI = 0.55\u20132.43; <i>p<\/i> = 0.710. Rates of complications such as sICH (mean \u00b1 SD 5 \u00b1 4.3 vs. 9 \u00b1 4.4; OR = 0.46; 95% CI = 0.08\u20132.66; <i>p<\/i> = 0.385) and SAH (mean \u00b1 SD 4 \u00b1 3.4 vs. 5 \u00b1 2.4; OR = 0.29; 95% CI = 0.03\u20133.09; <i>p<\/i> = 0.303) comparably low in both groups. <b><i>Conclusion:<\/i><\/b> Females achieved comparable functional outcomes compared with males after undergoing MT for BAO acute ischemic stroke. <\/jats:p>","DOI":"10.1159\/000524048","type":"journal-article","created":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T21:00:38Z","timestamp":1649365238000},"page":"639-646","source":"Crossref","is-referenced-by-count":12,"title":["Effect of Sex on Outcomes of Mechanical Thrombectomy in Basilar Artery Occlusion: A Multicentre Cohort Study"],"prefix":"10.1159","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1824-9077","authenticated-orcid":false,"given":"Benjamin 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L.L.","family":"Yeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2022,4,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000202582.29510.6b"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1385\/NCC:1:3:319"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.104954"}],"container-title":["Cerebrovascular 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