{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:40:37Z","timestamp":1780472437349,"version":"3.54.1"},"reference-count":16,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord Extra"],"abstract":"<jats:p>The ketogenic diet (KD) is a high-fat and low-carbohydrate diet with controlled amounts of protein. The use of drastic caloric restriction or ultralow-carbohydrate diets increases the production of ketone bodies, which are an alternative energy substrate in situations of insufficient glucose supply. Alzheimer\u2019s disease (AD) and Parkinson\u2019s disease are the most common neurodegenerative diseases in the world. It is believed that carbohydrate metabolism disorders may affect the progression of these diseases, as confirmed by both animal and human studies. Among patients with AD, the presence of ketone bodies in the body can improve cerebral circulation. Among Parkinson\u2019s patients, the presence of ketone bodies can reduce muscle tremor and stiffness, as well as improve cognitive function. The results of the research indicate that using a low-carbohydrate diet, including a KD, may have a beneficial effect on brain function in diseases that cause neuronal damage. <\/jats:p>","DOI":"10.1159\/000524331","type":"journal-article","created":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T21:00:41Z","timestamp":1653944441000},"page":"100-106","source":"Crossref","is-referenced-by-count":31,"title":["The Effect of the Ketogenic Diet on the Therapy of Neurodegenerative Diseases and Its Impact on Improving Cognitive Functions"],"prefix":"10.1159","volume":"12","author":[{"given":"Klaudia","family":"Grochowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Przeliorz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-019-01225-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2014.00133"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2262-17.2018"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.trci.2017.11.002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-12-137"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2010.10.006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.56.6.730"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0083940"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-181306"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27390"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2014.01.005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-018-1862-8"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00710"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-1959-9"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-56166-8"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.5604"}],"container-title":["Dementia and Geriatric Cognitive Disorders Extra"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524331","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524331","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:01:19Z","timestamp":1745424079000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000524331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,30]]},"references-count":16,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,10,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000524331","archive":["Portico"],"relation":{},"ISSN":["1664-5464"],"issn-type":[{"value":"1664-5464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,30]]}}}