{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T01:46:01Z","timestamp":1772502361255,"version":"3.50.1"},"reference-count":30,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Audiol Neurotol"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; The prognosis of Bell\u2019s palsy, idiopathic facial nerve palsy (FNP), is usually predicted by electroneuronography in subacute phase. However, it would be ideal to establish a reliable and objective examination applicable in acute phase to predict the prognosis of FNP. Immune-nutritional status (INS) calculated from peripheral blood examination is recently reported as the prognostic factor in various disease. However, the validity of INS as the prognostic factor in Bell\u2019s palsy is not well known. Thus, we conducted a retrospective study to investigate the usefulness of INS as prognostic predictors of Bell\u2019s palsy. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We reviewed the medical records of 79 patients with Bell\u2019s palsy and divided into two groups as \u201ccomplete recovery\u201d and \u201cincomplete recovery\u201d groups. Clinical features such as severity of FNP and INS, including neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR), prognostic nutritional index (PNI), and controlling nutrition status (CONUT) score, were assessed. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; In univariate analysis, statistically significant differences were observed in clinical score of facial movement, NLR, LMR, PNI, and CONUT score at the initial examination between the two groups (&lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). Furthermore, in multivariate analysis, statistically significant differences were also observed in facial movement score and PNI at the initial examination (&lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Immune and nutritional condition play important roles in the pathogenesis of Bell\u2019s palsy, suggesting that INS would be one of the useful prognostic factors in Bell\u2019s palsy. <\/jats:p>","DOI":"10.1159\/000524355","type":"journal-article","created":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T21:00:31Z","timestamp":1651784431000},"page":"418-426","source":"Crossref","is-referenced-by-count":5,"title":["Immune-Nutritional Status as a Novel Prognostic Predictor of Bell\u2019s Palsy"],"prefix":"10.1159","volume":"27","author":[{"given":"Kengo","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6273-8527","authenticated-orcid":false,"given":"Takaomi","family":"Kurioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motofumi","family":"Ohki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Asako","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Sano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taku","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2022,5,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.21639"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers6031670"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0646-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1096-9071(199803)54:3%3c162::aid-jmv3%3e3.0.co;2-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.610"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(88)90126-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-70252-2"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4445-z"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/1755-7682-5-2"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132488"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.12.064"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7305"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000150700.46377.96"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-017-0744-3"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000341583"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7874\/jao.2016.20.1.8"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182635417"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-1_part_1-199601010-00005"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2018.02.025"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.5551\/jat.31526"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2014.05.005"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.08.001"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.05.006"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31829b57df"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20329"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00599"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25583"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2019.09.034"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.04.018"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1177\/15330338211027910"}],"container-title":["Audiology and Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:01:28Z","timestamp":1745424088000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000524355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,9,12]]},"published-print":{"date-parts":[[2022,9,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000524355","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.19710640","asserted-by":"subject"}]},"ISSN":["1420-3030","1421-9700"],"issn-type":[{"value":"1420-3030","type":"print"},{"value":"1421-9700","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}