{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T08:03:16Z","timestamp":1777968196154,"version":"3.51.4"},"reference-count":25,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2022]]},"abstract":"<b><i>Introduction:<\/i><\/b> The purpose of the present study was to assess nasal mucociliary clearance (NMC) and sinonasal symptoms of healthcare professionals wearing filtering facepiece-3 (FFP3) respirators. <b><i>Methods:<\/i><\/b> This prospective cross-sectional study was conducted at a large tertiary care academic center. Thirty-four healthcare professionals working at a coronavirus disease-19 patient care unit were included in the study. Visual analog scale (VAS) scores of sinonasal symptoms (nasal discharge, postnasal discharge, nasal blockage, hyposmia, facial pain\/pressure, facial fullness, headache, fatigue, halitosis, cough) and the NMC times of the participants were assessed immediately before wearing FFP3 respirators and after 4 h of work with FFP3 respirators. <b><i>Results:<\/i><\/b> The mean age of the participants was 28.82 \u00b1 4.95 (range, 26\u201331) years. Twenty participants were female and 14 were male. After wearing the FFP3 respirators for 4 h, a statistically significant increase was observed in total VAS scores for all sinonasal symptoms and NMC times (<i>p<\/i> &#x3c; 0.001). When the VAS score of each sinonasal symptom was evaluated separately, a statistically significant increase was found for VAS scores of nasal discharge, postnasal discharge, nasal blockage, hyposmia, facial pain\/pressure, and facial fullness (<i>p<\/i> &#x3c; 0.05). <b><i>Conclusion:<\/i><\/b> The present study shows that nasal mucosal functions might be affected significantly after 4 h of using FFP3 respirators. The long-term effects and clinical significance of these short-term changes should be investigated on healthcare professionals in further studies. <\/jats:p>","DOI":"10.1159\/000524418","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T21:02:13Z","timestamp":1651525333000},"page":"406-411","source":"Crossref","is-referenced-by-count":5,"title":["Nasal Mucociliary Clearance and Sinonasal Symptoms in Healthcare Professionals Wearing FFP3 Respirators: A Prospective Cross-Sectional Study"],"prefix":"10.1159","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2820-8888","authenticated-orcid":false,"given":"Sel\u00e7uk","family":"Yildiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3681-5418","authenticated-orcid":false,"given":"Aykut","family":"Yankuncu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sema","family":"Zer Toros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c7i\u011fdem","family":"Tepe Karaca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/15459620801969998"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2010.01713.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17134624"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1080\/15298669191364875"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5606\/kbbihtisas.2014.58998"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/s0169-409x(01)00172-7"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3712-8"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2439-7"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.13e39.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/0007-0971(85)90003-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1080\/15298669191364631"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/15569527.2021.1900218"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2015.08.027"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.10.009"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2012.26.3716"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06254-7"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05717-w"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06457-y"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1979.120.4.739"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1977.43.1.46"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1995.tb00040.x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2235-3"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/s0898-6568(02)00143-2"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.2114\/jpa2.25.7"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20146"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524418","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/524418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:02:07Z","timestamp":1745424127000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000524418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":25,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,9,20]]},"published-print":{"date-parts":[[2022,9,27]]}},"URL":"https:\/\/doi.org\/10.1159\/000524418","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]}}}