{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:24:54Z","timestamp":1787793894697,"version":"build-2784847793"},"reference-count":16,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T00:00:00Z","timestamp":1676332800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T00:00:00Z","timestamp":1676332800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>Hidradenitis suppurativa (HS) is an inflammatory skin disease showing a chronic-remitting course. It has been rarely reported that long-term inflammation in HS could lead to serious complications like cutaneous squamous cell carcinoma. Cemiplimab is a fully human antibody immunotherapy that inhibits programmed cell death protein-1, approved for the treatment of locally advanced squamous cell carcinoma, or metastatic squamous cell carcinoma, in patients not eligible for curative surgery or radiotherapy. Herein, we report the case of a 56-year-old patient developing an invasive SCC on longstanding and unresponsive HS lesions successfully treated with cemiplimab. <\/jats:p>","DOI":"10.1159\/000525347","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T22:01:18Z","timestamp":1676412078000},"page":"35-39","source":"Crossref","is-referenced-by-count":8,"title":["Advanced Squamous Cell Carcinoma Developed on Chronic Hidradenitis Suppurativa, Successfully Treated with Cemiplimab: A Case Report"],"prefix":"10.1159","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4658-7391","authenticated-orcid":false,"given":"Angelo","family":"Ruggiero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9212-6601","authenticated-orcid":false,"given":"Wanda","family":"Lauro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Miano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Villani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0064-1874","authenticated-orcid":false,"given":"Gabriella","family":"Fabbrocini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8401-5730","authenticated-orcid":false,"given":"Claudio","family":"Marasca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2023,2,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000508669"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2021.33.1.68"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13756"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14673"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1771257"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13839"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.15570\/actaapa.2018.5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10020455"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/mc.23196"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1769828"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15102"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0903907"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12671"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.8.21.9921"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13006"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2019.1665026"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cde\/article-pdf\/15\/1\/35\/4113014\/000525347.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cde\/article-pdf\/15\/1\/35\/4113014\/000525347.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:03:57Z","timestamp":1745420637000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000525347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,14]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12,21]]}},"URL":"https:\/\/doi.org\/10.1159\/000525347","archive":["Portico"],"relation":{},"ISSN":["1662-6567"],"issn-type":[{"value":"1662-6567","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,14]]}}}