{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:34:08Z","timestamp":1747193648112,"version":"3.40.5"},"reference-count":16,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Malaria is known to be a significant risk factor and also a potential complicating factor during the treatment of lymphoid malignancy. There has not been a reported case of malaria reactivation that occurred weeks after cytotoxic chemotherapy completion, especially in non-endemic regions. Our patient was a 47-year-old man with a history of repeated falciparum malaria infection experiencing 2 months of progressive unilateral nasal blockage and recurrent anterior epistaxis, which was diagnosed as diffuse large B-cell lymphoma (DLBCL) through pathological examination. He was treated with six cycles of classical R-CHOP, resulting in complete remission. One month after remission, he experienced shivering, fever, sweating, and a return to normal temperature, which repeated irregularly for roughly 1 week. His laboratory result showed anaemia, leucopenia, and profound thrombocytopenia. Immunochromatographic testing (ICT) confirmed the diagnosis of falciparum malaria. This case was considered a relapse since our centre is not in the malaria-endemic region. He was cured with a combination of dihydroartemisinin-piperaquine and primaquine. Our case demonstrated the duality of malaria as potential aetiology and treatment complicating factor in DLBCL. <\/jats:p>","DOI":"10.1159\/000530337","type":"journal-article","created":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T21:27:03Z","timestamp":1687210023000},"page":"308-313","source":"Crossref","is-referenced-by-count":2,"title":["Malaria as Potential Aetiology and Treatment Complicating Factor in DLBCL Patient: A Case Report"],"prefix":"10.1159","author":[{"given":"Ibnu","family":"Purwanto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina Fitria","family":"Ariesta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9236-9435","authenticated-orcid":false,"given":"Susanna Hilda","family":"Hutajulu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bambang Purwanto","family":"Utomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doni Priambodo","family":"Wijisaksono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irianiwati","family":"Widodo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2023,5,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-1056"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-200002000-00008"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000118663"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-007-0742-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00911-11"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01759-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/nature06547"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2000.0751"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.07.019"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030080"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000449251"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-018-0561-0"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.19746\/j.cnki.issn.1009-2137.2022.05.019"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.5063"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3892\/ijo_00000323"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(86)81077-8"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cro\/article-pdf\/16\/1\/308\/4013241\/000530337.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cro\/article-pdf\/16\/1\/308\/4013241\/000530337.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:23:07Z","timestamp":1745421787000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000530337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,12]]},"references-count":16,"URL":"https:\/\/doi.org\/10.1159\/000530337","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.22651876","asserted-by":"subject"}]},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2023,5,12]]}}}