{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T18:19:18Z","timestamp":1755800358188,"version":"3.40.5"},"reference-count":84,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Introduction: Coronavirus disease 2019 (COVID-19), a global pandemic, has infected approximately 10% of the world\u2019s population. This comprehensive review aimed to determine the prevalence of various neurological disorders in COVID-19 without overlapping meta-analysis errors. Methods: We searched for meta-analyses on neurological disorders following COVID-19 published up to March 14, 2023. We obtained 1,184 studies, of which 44 meta-analyses involving 9,228,588 COVID-19 patients were finally included. After confirming the forest plot of each study and removing overlapping individual studies, a re-meta-analysis was performed using the random-effects model. Results: The summarized combined prevalence of each neurological disorder is as follows: stroke 3.39% (95% confidence interval, 1.50\u20135.27), dementia 6.41% (1.36\u201311.46), multiple sclerosis 4.00% (2.50\u20135.00), epilepsy 5.36% (\u22120.60\u201311.32), Parkinson\u2019s disease 0.67% (\u22121.11\u20132.45), encephalitis 0.66% (\u22120.44\u20131.77), and Guillain-Barr\u00e9 syndrome 3.83% (\u22120.13\u20137.80). In addition, the mortality risk of patients with comorbidities of COVID-19 is as follows: stroke OR 1.63 (1.23\u20132.03), epilepsy OR 1.71 (1.00\u20132.42), dementia OR 1.90 (1.31\u20132.48), Parkinson\u2019s disease OR 3.94 (\u22122.12\u201310.01). Conclusion: Our results show that the prevalence and mortality risk may increase in some neurological diseases during the COVID-19 pandemic. Future studies should elucidate the precise mechanisms for the link between COVID-19 and neurological diseases, determine which patient characteristics predispose them to neurological diseases, and consider potential global patient management. <\/jats:p>","DOI":"10.1159\/000530536","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T21:00:25Z","timestamp":1681333225000},"page":"129-147","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence and Mortality Risk of Neurological Disorders during the COVID-19 Pandemic: An Umbrella Review of the Current Evidence"],"prefix":"10.1159","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4272-7489","authenticated-orcid":false,"given":"Jong Mi","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wongi","family":"Woo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang 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