{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:34:09Z","timestamp":1747193649455,"version":"3.40.5"},"reference-count":13,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>A 28-year-old woman presented to eye casualty with signs and symptoms suggestive of optic neuritis following a recent COVID-19 vaccination (the Moderna mRNA-1273 vaccine). The best corrected visual acuity was 6\/15 in the right eye and 6\/6 in the left eye with a relative afferent pupillary defect in the right eye. Following examination and investigation, she was found to fit the McDonald criteria for multiple sclerosis and was commenced on disease-modifying therapy. Demyelinating events have been identified to occur following COVID-19 vaccinations. In this case, we have found that the Moderna mRNA-1273 vaccine could have contributed to the development of optic neuritis following a second dose of the vaccine. <\/jats:p>","DOI":"10.1159\/000531526","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T21:16:23Z","timestamp":1697663783000},"page":"394-399","source":"Crossref","is-referenced-by-count":1,"title":["Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report"],"prefix":"10.1159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4760-0885","authenticated-orcid":false,"given":"Edward","family":"Saxton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binita","family":"Panchasara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Sarangapani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2023,8,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057755"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-72167-3_11"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2017.243"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2021.577765"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22366"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.inat.2021.101320"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2018.10.012"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2020.108480"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/358155a0"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3282f0ad25"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21176236"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2021.10.015"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.4.504"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cop\/article-pdf\/14\/1\/394\/3990993\/000531526.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cop\/article-pdf\/14\/1\/394\/3990993\/000531526.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:36:14Z","timestamp":1745422574000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000531526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,23]]},"references-count":13,"URL":"https:\/\/doi.org\/10.1159\/000531526","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.23807337","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"type":"electronic","value":"1663-2699"}],"subject":[],"published":{"date-parts":[[2023,8,23]]}}}