{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:34:15Z","timestamp":1747193655949,"version":"3.40.5"},"reference-count":33,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Introduction: VACTERL is defined as 3 or more of the following congenital defects: vertebral, anorectal, cardiac, tracheoesophageal (TE), renal, and limb. The purpose of this study was to create an easy-to-use assessment tool to help providers counsel expecting families regarding the likelihood of additional anomalies and postnatal outcomes. Methods: Employing the Kids\u2019 Inpatient Database from 2003\u20132016, neonates (&amp;lt;29 days old) with VACTERL were identified using ICD-9-CM and ICD-10-CM codes. For each unique combination of VACTERL, multivariable logistic regression was used to estimate inpatient mortality, and Poisson regression was used to estimate length-of-stay during the initial hospitalization. Results: The assessment tool used in this study is available at &lt;ext-link ext-link-type=\"uri\" xlink:href=\"https:\/\/choc-trauma.shinyapps.io\/VACTERL\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\"&gt;https:\/\/choc-trauma.shinyapps.io\/VACTERL&lt;\/ext-link&gt;. 1,886 of 11,813,782 (0.016%) neonates presented with VACTERL. 32% weighed &amp;lt;1,750 g, and 239 (12.7%) died prior to discharge. Associated with mortality were limb anomaly (1.8 [1.01\u20133.22], p &amp;lt; 0.05), prematurity (1.99 [1.14\u20133.47], p &amp;lt; 0.02), and weight &amp;lt;1,750 g (2.19 [1.25\u20133.82], p &amp;lt; 0.01). Median length-of-stay was 14 days (IQR: 7-32). Associated with increased length-of-stay were cardiac defect (1.47 [1.37\u20131.56], p &amp;lt; 0.001), vertebral anomaly (1.1 [1.05\u20131.14], p &amp;lt; 0.001), TE fistula (1.73 [1.66\u20131.81], p &amp;lt; 0.001), anorectal malformation (1.12 [1.07\u20131.16], p &amp;lt; 0.001), and weight &amp;lt;1,750 g (1.65 [1.57\u20131.73], p &amp;lt; 0.001). Conclusion: This novel assessment tool may help providers counsel families confronting a VACTERL diagnosis. <\/jats:p>","DOI":"10.1159\/000531611","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T21:01:27Z","timestamp":1691614887000},"page":"368-375","source":"Crossref","is-referenced-by-count":0,"title":["A Novel VACTERL Assessment Tool to Facilitate Counseling for Expectant Families"],"prefix":"10.1159","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6642-690X","authenticated-orcid":false,"given":"John S.","family":"Riley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Schomberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Mantha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yigit 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