{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:21:24Z","timestamp":1790288484073,"version":"4.1.0"},"reference-count":10,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T00:00:00Z","timestamp":1691712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>A 13-year-old was admitted to our clinic complaining about a vision loss of over 2 weeks. Bilateral optic disc edema, peripapillary flame-shaped hemorrhages, macular star pattern exudates, and cotton wool spots were found in fundoscopic examination. The OCT exam showed bilaterally serous retinal detachments in sub-foveal region with intraretinal exudates. A pediatric examination found a high systemic hypertension of 230\/140 mm Hg, and laboratory tests revealed increased levels of plasmatic and urinary catecholamines. An abdominal MRI showed a left suprarenal pheochromocytoma and the child underwent an adrenalectomy urgently. Informed patient consent was obtained from legal guardians to publish clinical images. Malignant hypertension (MHT) as a result of a pheochromocytoma is an extremely rare condition in childhood. MHT crisis represents a potential life-threatening event and an immediate treatment can prevent a multi-organ failure, including the eyes. An early diagnosis of MHT by fundus examination can lead to a completely favorable ophthalmological evolution and entirely functional recovery. <\/jats:p>","DOI":"10.1159\/000531663","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T21:16:31Z","timestamp":1697663791000},"page":"348-352","source":"Crossref","is-referenced-by-count":2,"title":["Hypertensive Retinopathy as a Presenting Sign of Pheochromocytoma with Malignant Hypertension: A Child Case"],"prefix":"10.1159","author":[{"given":"Filippo","family":"Billia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Palmieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Maccari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4347-6573","authenticated-orcid":false,"given":"Feliciana","family":"Menna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Consigli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2023,8,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2147\/OAEM.S32809"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-197412000-00004"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2013.839812"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199210000-00018"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra032865"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.65.3.153"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20070701-06"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.164053"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/adc.85.5.401"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2011.09.010"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cop\/article-pdf\/14\/1\/348\/3985916\/000531663.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cop\/article-pdf\/14\/1\/348\/3985916\/000531663.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:37:40Z","timestamp":1745422660000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000531663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,11]]},"references-count":10,"URL":"https:\/\/doi.org\/10.1159\/000531663","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.23694570","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,11]]}}}