{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T04:33:04Z","timestamp":1781065984383,"version":"3.54.1"},"reference-count":14,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>Nocardia spp. are gram positive, aerobic, weakly acid-fast bacteria. Nocardia spp. keratitis is a rare ocular infection classically described following corneal injury or vegetative and soil exposure. However, keratitis caused by Nocardia africana had never been reported in the literature. We first reported a 70-year-old male who had a traumatic ocular injury to his left eye a month ago. With his complaint of left eye pain, reduced vision, and light sensitivity, the slit-lamp biomicroscopy showed the superficial multi-lobulated epithelial infiltration located at the inferior cornea with a positive fluorescein stain. Microscopic workup from corneal specimens demonstrated dry and chalky white colonies on blood agar and Lowenstein-Jensen media resembling Nocardia spp. The MALDI-TOF MS analyses using VITEK\u00ae MS exhibited N. africana. The corneal lesion was treated with 2% amikacin topical eye drops and responded well. The careful history-taking, precise clinical examinations, and meticulous microscopic assessment were the cornerstones of diagnosis. Definite diagnosis and timely treatment were essential to prevention of ocular morbidity in N. africana. <\/jats:p>","DOI":"10.1159\/000533906","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T21:16:47Z","timestamp":1697663807000},"page":"507-512","source":"Crossref","is-referenced-by-count":3,"title":["A Case of Nocardia africana-Related Keratitis"],"prefix":"10.1159","author":[{"given":"Winai","family":"Chaidaroon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prangchanok","family":"Sawetwong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirinya","family":"Manochomphu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2023,10,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1099\/jmmcr.0.005175"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s12348-020-00228-w"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.2.625-630.2001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-003-0046-7"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_564_16"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000462"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01419-17"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-6257(00)00207-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.10.037"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-022-02500-5"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13182"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0144878"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2016\/15039.7144"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32832c3bcc"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cop\/article-pdf\/14\/1\/507\/4011208\/000533906.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cop\/article-pdf\/14\/1\/507\/4011208\/000533906.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:41:13Z","timestamp":1745422873000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000533906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,6]]},"references-count":14,"URL":"https:\/\/doi.org\/10.1159\/000533906","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.24235087","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,6]]}}}