{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:55:17Z","timestamp":1784919317403,"version":"3.55.0"},"reference-count":0,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2023]]},"abstract":"<b><i>Introduction:<\/i><\/b> Slit ventricle syndrome (SVS) remains a challenging problem in the early-shunted paediatric population. Various surgical and non-surgical treatments have been devised for this condition. However, there is currently no gold standard for its optimal management. Among various treatment modalities, subtemporal decompression (STD) is often performed as a last resort. We present our experience of STD in paediatric patients with SVS in whom initial treatment with programmable valves and anti-syphon device were not successful. <b><i>Methods:<\/i><\/b> This is a single-centre retrospective observational study and survival analysis. Patients who underwent STD for SVS were included. Pre- and post-operative imaging data and clinical outcomes were collected. <b><i>Results:<\/i><\/b> There were 20 patients (12 M, 8 F) with a mean age of 9 years (SD: 4) at first STD. 90% (<i>n<\/i> = 18) of patients had multiple shunt revisions pre-STD. At first STD, 70% (<i>n<\/i> = 14) and 30% (<i>n<\/i> = 6) of patients had unilateral or bilateral STD, respectively. STD led to a reduction in the frequency of shunt revisions in 60% (<i>n<\/i> = 12) of patients. The median time required before further STD, shunt surgery, or cranial vault surgery was 14 months. The median time before a further STD was required (either revision or contralateral side) was 89 months. At a median follow-up of 66.5 months (range: 1\u2013159), 65% (<i>n<\/i> = 13) of patients had improvement in symptoms. <b><i>Conclusions:<\/i><\/b> A large proportion of patients with persistent SVS symptoms, refractory to multiple shunt revisions, benefitted from STD in combination with shunt optimization. It was also safe and well-tolerated. Therefore, in patients who have multiple failed shunts, STD may reduce the morbidity associated with further shunt revisions and can significantly improve symptomatology. <\/jats:p>","DOI":"10.1159\/000534611","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T21:00:35Z","timestamp":1697576435000},"page":"420-428","source":"Crossref","is-referenced-by-count":3,"title":["Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis"],"prefix":"10.1159","volume":"58","author":[{"given":"Mehdi","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Louise","family":"Craven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Zubair","family":"Tahir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2023,10,17]]},"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/pne\/article-pdf\/doi\/10.1159\/000534611\/4046197\/000534611.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/pne\/article-pdf\/doi\/10.1159\/000534611\/4046197\/000534611.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:48:50Z","timestamp":1745423330000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000534611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,12,12]]},"published-print":{"date-parts":[[2023,12,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000534611","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}