{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:11:33Z","timestamp":1790629893638,"version":"4.1.0"},"reference-count":36,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerontology"],"published-print":{"date-parts":[[2024]]},"abstract":"<b><i>Introduction:<\/i><\/b> This study aimed to evaluate the association of respiratory muscle strength with sarcopenia and its indicators in the oldest old. <b><i>Methods:<\/i><\/b> Maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), and sarcopenia-related factors (handgrip strength and appendicular lean mass) were evaluated in a cohort of <i>n<\/i> = 286 (45.5% female) non-frail, community-dwelling persons aged 83.6 \u00b1 3.0 years (age range 80\u201397 years). <b><i>Results:<\/i><\/b> The sample presented a sarcopenia prevalence of 32.2%. Sarcopenic subjects showed comparable MIP and MEP as non-sarcopenic ones (female: MIP 43.9 \u00b1 18.9 vs. 50.3 \u00b1 19.5, <i>p<\/i> = 0.053; MEP 63.0 \u00b1 23.0 vs. 69.2 \u00b1 19.1, <i>p<\/i> = 0.067; male: MIP, 65.1 \u00b1 24.4 vs. 64.4 \u00b1 23.9, <i>p<\/i> = 0.433; MEP 87.7 \u00b1 33.3 vs. 93.8 \u00b1 30.9, <i>p<\/i> = 0.124). Statistically significant but very low associations were found between grip strength and MIP (<i>r<\/i> = 0.193 for male, <i>p<\/i> &lt; 0.05 and <i>r<\/i> = 0.257 for female participants, <i>p<\/i> &lt; 0.01) and MEP (<i>r<\/i> = 0.200 for male, <i>p<\/i> &lt; 0.01 and <i>r<\/i> = 0.191 for female participants, <i>p<\/i> &lt; 0.05). Lean mass was significantly correlated to MIP and MEP in female (<i>r<\/i> = 0.253, <i>p<\/i> &lt; 0.01 and <i>r<\/i> = 0.343, <i>p<\/i> &lt; 0.01, respectively), whereas this association was not found in male participants. Grip strength was the only statistically significant predictor of MEP (<i>r<\/i><sup>2<\/sup> = 0.212, <i>p<\/i> &lt; 0.001), while MIP was independently predicted by age, male sex, and grip strength (<i>r<\/i><sup>2<\/sup> = 0.177, <i>p<\/i> &lt; 0.001). <b><i>Conclusions:<\/i><\/b> Peripheral muscle strength is a statistically significant, albeit weak predictor for respiratory muscle strength in well-functioning, community-dwelling persons aged 80+. When confronted to a low grip strength, one should be aware of concomitant respiratory muscle weakness, as this is a known risk factor for atelectasis and pneumonia. Given the relatively low association with handgrip strength, respiratory muscle strength testing might be indicated. <\/jats:p>","DOI":"10.1159\/000536361","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T22:00:43Z","timestamp":1711576843000},"page":"526-535","source":"Crossref","is-referenced-by-count":2,"title":["Respiratory Muscle Strength Is Related to Handgrip Performance in Community-Dwelling Persons Aged 80+ from the BUTTERFLY 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