{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T15:18:37Z","timestamp":1760800717687,"version":"3.40.4"},"reference-count":43,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroepidemiology"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; The long-term cognitive outcomes after transient global amnesia (TGA) have been contradictory in the literature. Our study aimed to longitudinally investigate the association between TGA and incident dementia using long-term data from a nationwide population-based cohort in South Korea. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; The study population was recruited between 2002 and 2020 using the International Classification of Diseases (Tenth Revision; ICD-10) codes from the Korean National Health Insurance Service database. The cumulative incidence curve was plotted to compare the incidence of dementia between the TGA (ICD-10 code G45.4; &lt;i&gt;n&lt;\/i&gt; = 10,276) and non-TGA (&lt;i&gt;n&lt;\/i&gt; = 27,389) groups, determined using 1:3 propensity score matching. Using Cox proportional hazard regression models, we obtained crude and adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for the incident dementia in patients with TGA compared to non-TGA controls. To examine independent variables determining dementia in the TGA group, logistic regression analysis was performed, and adjusted odds ratios (aORs) and 95% CIs were calculated. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The TGA group had a significantly higher cumulative incidence of dementia than the non-TGA group (&lt;i&gt;p&lt;\/i&gt; &amp;lt; 0.001, log-rank test). TGA was significantly associated with incident dementia in the univariate and multivariate Cox models (HR 1.34, 95% CI 1.28\u20131.39 and aHR 1.40, 95% CI 1.34\u20131.46, respectively). The adjusted logistic regression for incident dementia in the TGA group showed that age (per 1 year, aOR 1.09, 95% CI 1.09\u20131.10), female sex (aOR 1.31, 95% CI 1.18\u20131.45), diabetes (aOR 1.21, 95% CI 1.08\u20131.35), stroke (aOR 1.30, 95% CI 1.16\u20131.46), depression (aOR 1.53, 95% CI 1.33\u20131.76), anxiety (aOR 1.24, 95% CI 1.01\u20131.39), and rural residence (aOR 1.24, 95% CI 1.10\u20131.41) were independently associated with incident dementia. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Our results suggest a longitudinal association of TGA with incident dementia. <\/jats:p>","DOI":"10.1159\/000536529","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T22:00:27Z","timestamp":1709762427000},"page":"247-255","source":"Crossref","is-referenced-by-count":2,"title":["Increased Risk of Dementia after Transient Global Amnesia: A Nationwide Population-Based, Longitudinal Follow-Up Study in South 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