{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:05:52Z","timestamp":1791579952616,"version":"4.3.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Primary splenic lymphoma is a rare lymphoproliferative disorder that involves the spleen, exhibits diverse clinical presentations, and lacks a clear consensus in terms of management strategies. &lt;b&gt;&lt;i&gt;Case Presentation:&lt;\/i&gt;&lt;\/b&gt; We present the case of a 52-year-old patient with a complex medical history marked by multiple chronic medical conditions. The patient was diagnosed with primary splenic lymphoma, specifically the diffuse large B-cell subtype. Treatment for our patient involved a shortened course of chemotherapy (4 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone [R-CHOP] followed by two doses of rituximab) due to issues related to compliance and treatment-related complications. This was followed by consolidative radiotherapy without resorting to splenectomy. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Remarkably, despite using a shortened course of R-CHOP, the patient achieved complete resolution, and a positron emission tomography scan conducted at the end of the 6-month posttreatment period confirmed sustained complete remission.<\/jats:p>","DOI":"10.1159\/000537780","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T17:00:34Z","timestamp":1709830834000},"page":"447-453","source":"Crossref","is-referenced-by-count":5,"title":["Primary Splenic Diffuse Large B-Cell Lymphoma: A Case Report and Literature Review of a Rare Condition"],"prefix":"10.1159","volume":"17","author":[{"given":"Mohammed Najdat","family":"Seijari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samer","family":"Kaspo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awni","family":"Alshurafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amro","family":"Elfaieg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Elkourashy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19901215)66:12<2612::aid-cncr2820661225>3.0.co;2-q"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3109\/10428199309148547"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2010.0026"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23433"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19881001)62:7<1433::aid-cncr2820620731>3.0.co;2-v"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1081\/cnv-120002492"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.12145"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-019-03628-8"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jha2.642"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4081\/rt.2011.e25"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29487"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-09-271437"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v4.i12.385"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20150400"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)33008-9"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-023-05171-z"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159\/000012104"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2017.12.002"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/cro\/article-pdf\/17\/1\/447\/4177218\/000537780.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/cro\/article-pdf\/17\/1\/447\/4177218\/000537780.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T11:06:33Z","timestamp":1745406393000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000537780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,7]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000537780","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.25288024","asserted-by":"subject"}],"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3654535\/v1","asserted-by":"object"}]},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,7]]}}}