{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:08:13Z","timestamp":1781104093353,"version":"3.54.1"},"reference-count":18,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Granulomatous mycosis fungoides (GMF) is a rare form of cutaneous T-cell lymphoma characterized by a granulomatous inflammatory infiltrate. &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; The impact of granulomatous inflammation on the prognosis of the disease remains controversial as there have been both favorable and unfavorable outcomes documented. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We performed a systematic review of 116 GMF cases previously described in the literature. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; In contrast to the classic Alibert-Bazin type of mycosis fungoides (MF), cutaneous lesions in GMF tend to involve distal extremities (lower legs, feet, hands) early in the disease course. In the literature, 30% of GMF patients developed organ metastasis, most frequently to the lung. The median time to stage progression was 25 months. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; GMF is an aggressive form of MF. Therefore, screening for distant metastases should be considered at presentation and repeated during follow-up. <\/jats:p>","DOI":"10.1159\/000537893","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T06:27:17Z","timestamp":1709879237000},"page":"468-473","source":"Crossref","is-referenced-by-count":3,"title":["Early Organ Metastasis in Granulomatous Mycosis Fungoides: A Systematic Review"],"prefix":"10.1159","volume":"240","author":[{"given":"Melika","family":"Motamedi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maggie Z.X.","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Deschenes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jori","family":"Hardin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Sterrett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley","family":"Street","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minakshi","family":"Taparia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Mahe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Ferrara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Barrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Gniadecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1970.tb06839.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2015.05.010"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.03.036"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198802000-00002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20153460"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198304000-00012"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930140409"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2008.46"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2010.01577.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-11-881268"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008946.pub3"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.27.7665"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2019-126246"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20175099"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.10.012"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2012.3198"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22567"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2015.05.008"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/drm\/article-pdf\/240\/3\/468\/4240532\/000537893.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/drm\/article-pdf\/240\/3\/468\/4240532\/000537893.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:07:25Z","timestamp":1745420845000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000537893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,6,11]]},"published-print":{"date-parts":[[2024,6,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000537893","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.25311274","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]}}}